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Structural and Molecular Basis for Mitochondrial DNA Replication and Transcription in Health and Antiviral Drug Toxicity

Human mitochondrial DNA (mtDNA) is a 16.9 kbp double-stranded, circular DNA, encoding subunits of the oxidative phosphorylation electron transfer chain and essential RNAs for mitochondrial protein translation. The minimal human mtDNA replisome is composed of the DNA helicase Twinkle, DNA polymerase...

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Detalles Bibliográficos
Autores principales:	Park, Joon, Baruch-Torres, Noe, Yin, Y. Whitney
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961925/ https://www.ncbi.nlm.nih.gov/pubmed/36838782 http://dx.doi.org/10.3390/molecules28041796

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