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Development of a Reinforcement Learning Algorithm to Optimize Corticosteroid Therapy in Critically Ill Patients with Sepsis
Background: The optimal indication, dose, and timing of corticosteroids in sepsis is controversial. Here, we used reinforcement learning to derive the optimal steroid policy in septic patients based on data on 3051 ICU admissions from the AmsterdamUMCdb intensive care database. Methods: We identifie...
Autores principales: | Bologheanu, Razvan, Kapral, Lorenz, Laxar, Daniel, Maleczek, Mathias, Dibiasi, Christoph, Zeiner, Sebastian, Agibetov, Asan, Ercole, Ari, Thoral, Patrick, Elbers, Paul, Heitzinger, Clemens, Kimberger, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9961939/ https://www.ncbi.nlm.nih.gov/pubmed/36836046 http://dx.doi.org/10.3390/jcm12041513 |
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