Sphingoid Bases Regulate the Sigma-1 Receptor—Sphingosine and N,N’-Dimethylsphingosine Are Endogenous Agonists

Both bioactive sphingolipids and Sigma-1 receptor (S1R) chaperones occur ubiquitously in mammalian cell membranes. Endogenous compounds that regulate the S1R are important for controlling S1R responses to cellular stress. Herein, we interrogated the S1R in intact Retinal Pigment Epithelial cells (AR...

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Detalles Bibliográficos
Autores principales: Li, Jing, Satyshur, Kenneth A., Guo, Lian-Wang, Ruoho, Arnold E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962145/
https://www.ncbi.nlm.nih.gov/pubmed/36834510
http://dx.doi.org/10.3390/ijms24043103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962145/
https://www.ncbi.nlm.nih.gov/pubmed/36834510
http://dx.doi.org/10.3390/ijms24043103

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