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Human Immunodeficiency Virus and Uveitis

Uveitis is one of the most common ocular complications in people living with the Human immunodeficiency virus (HIV) and can be classified into HIV-induced uveitis, co-infection related uveitis, immune recovery uveitis, and drug-induced uveitis. The introduction of antiretroviral therapy has consider...

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Autores principales: Yang, Mingming, Kamoi, Koju, Zong, Yuan, Zhang, Jing, Ohno-Matsui, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962278/
https://www.ncbi.nlm.nih.gov/pubmed/36851658
http://dx.doi.org/10.3390/v15020444
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author Yang, Mingming
Kamoi, Koju
Zong, Yuan
Zhang, Jing
Ohno-Matsui, Kyoko
author_facet Yang, Mingming
Kamoi, Koju
Zong, Yuan
Zhang, Jing
Ohno-Matsui, Kyoko
author_sort Yang, Mingming
collection PubMed
description Uveitis is one of the most common ocular complications in people living with the Human immunodeficiency virus (HIV) and can be classified into HIV-induced uveitis, co-infection related uveitis, immune recovery uveitis, and drug-induced uveitis. The introduction of antiretroviral therapy has considerably changed the incidence, diagnosis, and treatment of different types of HIV-related uveitis. Furthermore, the specific immune condition of patients infected with HIV makes diagnosing HIV-related uveitis difficult. Recent studies have focused on the growing prevalence of syphilis/tuberculosis co-infection in uveitis. Simultaneously, more studies have demonstrated that HIV can directly contribute to the incidence of uveitis. However, the detailed mechanism has not been studied. Immune recovery uveitis is diagnosed by exclusion, and recent studies have addressed the role of biomarkers in its diagnosis. This review highlights recent updates on HIV-related uveitis. Furthermore, it aims to draw the attention of infectious disease physicians and ophthalmologists to the ocular health of patients infected with HIV.
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spelling pubmed-99622782023-02-26 Human Immunodeficiency Virus and Uveitis Yang, Mingming Kamoi, Koju Zong, Yuan Zhang, Jing Ohno-Matsui, Kyoko Viruses Review Uveitis is one of the most common ocular complications in people living with the Human immunodeficiency virus (HIV) and can be classified into HIV-induced uveitis, co-infection related uveitis, immune recovery uveitis, and drug-induced uveitis. The introduction of antiretroviral therapy has considerably changed the incidence, diagnosis, and treatment of different types of HIV-related uveitis. Furthermore, the specific immune condition of patients infected with HIV makes diagnosing HIV-related uveitis difficult. Recent studies have focused on the growing prevalence of syphilis/tuberculosis co-infection in uveitis. Simultaneously, more studies have demonstrated that HIV can directly contribute to the incidence of uveitis. However, the detailed mechanism has not been studied. Immune recovery uveitis is diagnosed by exclusion, and recent studies have addressed the role of biomarkers in its diagnosis. This review highlights recent updates on HIV-related uveitis. Furthermore, it aims to draw the attention of infectious disease physicians and ophthalmologists to the ocular health of patients infected with HIV. MDPI 2023-02-05 /pmc/articles/PMC9962278/ /pubmed/36851658 http://dx.doi.org/10.3390/v15020444 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yang, Mingming
Kamoi, Koju
Zong, Yuan
Zhang, Jing
Ohno-Matsui, Kyoko
Human Immunodeficiency Virus and Uveitis
title Human Immunodeficiency Virus and Uveitis
title_full Human Immunodeficiency Virus and Uveitis
title_fullStr Human Immunodeficiency Virus and Uveitis
title_full_unstemmed Human Immunodeficiency Virus and Uveitis
title_short Human Immunodeficiency Virus and Uveitis
title_sort human immunodeficiency virus and uveitis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962278/
https://www.ncbi.nlm.nih.gov/pubmed/36851658
http://dx.doi.org/10.3390/v15020444
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