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Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1)

The movement of viruses in aquatic systems is rarely studied over large geographic scales. Oceanic currents, host migration, latitude-based variation in climate, and resulting changes in host life history are all potential drivers of virus connectivity, adaptation, and genetic structure. To expand o...

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Autores principales: Zhao, Mingli, Plough, Louis V., Behringer, Donald C., Bojko, Jamie, Kough, Andrew S., Alper, Nathaniel W., Xu, Lan, Schott, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962310/
https://www.ncbi.nlm.nih.gov/pubmed/36851777
http://dx.doi.org/10.3390/v15020563
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author Zhao, Mingli
Plough, Louis V.
Behringer, Donald C.
Bojko, Jamie
Kough, Andrew S.
Alper, Nathaniel W.
Xu, Lan
Schott, Eric J.
author_facet Zhao, Mingli
Plough, Louis V.
Behringer, Donald C.
Bojko, Jamie
Kough, Andrew S.
Alper, Nathaniel W.
Xu, Lan
Schott, Eric J.
author_sort Zhao, Mingli
collection PubMed
description The movement of viruses in aquatic systems is rarely studied over large geographic scales. Oceanic currents, host migration, latitude-based variation in climate, and resulting changes in host life history are all potential drivers of virus connectivity, adaptation, and genetic structure. To expand our understanding of the genetic diversity of Callinectes sapidus reovirus 1 (CsRV1) across a broad spatial and host life history range of its blue crab host (Callinectes sapidus), we obtained 22 complete and 96 partial genomic sequences for CsRV1 strains from the US Atlantic coast, Gulf of Mexico, Caribbean Sea, and the Atlantic coast of South America. Phylogenetic analyses of CsRV1 genomes revealed that virus genotypes were divided into four major genogroups consistent with their host geographic origins. However, some CsRV1 sequences from the US mid-Atlantic shared high genetic similarity with the Gulf of Mexico genotypes, suggesting potential human-mediated movement of CsRV1 between the US mid-Atlantic and Gulf coasts. This study advances our understanding of how climate, coastal geography, host life history, and human activity drive patterns of genetic structure and diversity of viruses in marine animals and contributes to the capacity to infer broadscale host population connectivity in marine ecosystems from virus population genetic data.
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spelling pubmed-99623102023-02-26 Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1) Zhao, Mingli Plough, Louis V. Behringer, Donald C. Bojko, Jamie Kough, Andrew S. Alper, Nathaniel W. Xu, Lan Schott, Eric J. Viruses Article The movement of viruses in aquatic systems is rarely studied over large geographic scales. Oceanic currents, host migration, latitude-based variation in climate, and resulting changes in host life history are all potential drivers of virus connectivity, adaptation, and genetic structure. To expand our understanding of the genetic diversity of Callinectes sapidus reovirus 1 (CsRV1) across a broad spatial and host life history range of its blue crab host (Callinectes sapidus), we obtained 22 complete and 96 partial genomic sequences for CsRV1 strains from the US Atlantic coast, Gulf of Mexico, Caribbean Sea, and the Atlantic coast of South America. Phylogenetic analyses of CsRV1 genomes revealed that virus genotypes were divided into four major genogroups consistent with their host geographic origins. However, some CsRV1 sequences from the US mid-Atlantic shared high genetic similarity with the Gulf of Mexico genotypes, suggesting potential human-mediated movement of CsRV1 between the US mid-Atlantic and Gulf coasts. This study advances our understanding of how climate, coastal geography, host life history, and human activity drive patterns of genetic structure and diversity of viruses in marine animals and contributes to the capacity to infer broadscale host population connectivity in marine ecosystems from virus population genetic data. MDPI 2023-02-18 /pmc/articles/PMC9962310/ /pubmed/36851777 http://dx.doi.org/10.3390/v15020563 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhao, Mingli
Plough, Louis V.
Behringer, Donald C.
Bojko, Jamie
Kough, Andrew S.
Alper, Nathaniel W.
Xu, Lan
Schott, Eric J.
Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1)
title Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1)
title_full Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1)
title_fullStr Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1)
title_full_unstemmed Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1)
title_short Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1)
title_sort cross-hemispheric genetic diversity and spatial genetic structure of callinectes sapidus reovirus 1 (csrv1)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962310/
https://www.ncbi.nlm.nih.gov/pubmed/36851777
http://dx.doi.org/10.3390/v15020563
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