Cardiac-Specific Expression of Cre Recombinase Leads to Age-Related Cardiac Dysfunction Associated with Tumor-like Growth of Atrial Cardiomyocyte and Ventricular Fibrosis and Ferroptosis

Transgenic expression of Cre recombinase driven by a specific promoter is normally used to conditionally knockout a gene in a tissue- or cell-type-specific manner. In αMHC-Cre transgenic mouse model, expression of Cre recombinase is controlled by the myocardial-specific α-myosin heavy chain (αMHC) p...

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Detalles Bibliográficos
Autores principales: Li, Zhongguang, Duan, Qinchun, Cui, Ying, Jones, Odell D., Shao, Danyang, Zhang, Jianfei, Gao, Yuru, Cao, Xixi, Wang, Shulin, Li, Jiali, Lei, Xinjuan, Zhang, Wei, Wang, Liyang, Zhou, Xin, Xu, Mengmeng, Liu, Yingli, Ma, Jianjie, Xu, Xuehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962429/
https://www.ncbi.nlm.nih.gov/pubmed/36834504
http://dx.doi.org/10.3390/ijms24043094

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