Secukinumab and Black Garlic Downregulate OPG/RANK/RANKL Axis and Devitalize Myocardial Interstitial Fibrosis Induced by Sunitinib in Experimental Rats

Sunitinib has been associated with several cardiotoxic effects such as cardiac fibrosis. The present study was designed to explore the role of interleukin (IL)-17 in sunitinib-induced myocardial fibrosis (MF) in rats and whether its neutralization and/or administration of black garlic (BG), a form o...

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Detalles Bibliográficos
Autores principales: Mohamad, Hoda E., Asker, Mervat E., Shaheen, Mohamed A., Baraka, Nourhan M., Fantoukh, Omer I., Alqahtani, Abdulaziz, Salama, Alaa E., Mahmoud, Yasmin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962443/
https://www.ncbi.nlm.nih.gov/pubmed/36836664
http://dx.doi.org/10.3390/life13020308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962443/
https://www.ncbi.nlm.nih.gov/pubmed/36836664
http://dx.doi.org/10.3390/life13020308

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