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Secukinumab and Black Garlic Downregulate OPG/RANK/RANKL Axis and Devitalize Myocardial Interstitial Fibrosis Induced by Sunitinib in Experimental Rats
Sunitinib has been associated with several cardiotoxic effects such as cardiac fibrosis. The present study was designed to explore the role of interleukin (IL)-17 in sunitinib-induced myocardial fibrosis (MF) in rats and whether its neutralization and/or administration of black garlic (BG), a form o...
Autores principales: | Mohamad, Hoda E., Asker, Mervat E., Shaheen, Mohamed A., Baraka, Nourhan M., Fantoukh, Omer I., Alqahtani, Abdulaziz, Salama, Alaa E., Mahmoud, Yasmin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962443/ https://www.ncbi.nlm.nih.gov/pubmed/36836664 http://dx.doi.org/10.3390/life13020308 |
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