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DOCK2 Mutation and Recurrent Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome resulting from uncontrolled hyper-inflammation, excessive immune system activation, and elevated levels of inflammatory cytokines. HLH can be caused by the inability to downregulate activated macrophages by natural killer (NK) and CD8 cytotoxic...

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Detalles Bibliográficos
Autores principales: Reiff, Daniel D., Zhang, Mingce, Cron, Randy Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962445/
https://www.ncbi.nlm.nih.gov/pubmed/36836791
http://dx.doi.org/10.3390/life13020434

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