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Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review

Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democr...

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Autores principales: Anwar, Faheem, Haider, Fatima, Khan, Sarmir, Ahmad, Ibrar, Ahmed, Naveed, Imran, Muhammad, Rashid, Summya, Ren, Zhi-Guang, Khattak, Saadullah, Ji, Xin-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962527/
https://www.ncbi.nlm.nih.gov/pubmed/36836879
http://dx.doi.org/10.3390/life13020522
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author Anwar, Faheem
Haider, Fatima
Khan, Sarmir
Ahmad, Ibrar
Ahmed, Naveed
Imran, Muhammad
Rashid, Summya
Ren, Zhi-Guang
Khattak, Saadullah
Ji, Xin-Ying
author_facet Anwar, Faheem
Haider, Fatima
Khan, Sarmir
Ahmad, Ibrar
Ahmed, Naveed
Imran, Muhammad
Rashid, Summya
Ren, Zhi-Guang
Khattak, Saadullah
Ji, Xin-Ying
author_sort Anwar, Faheem
collection PubMed
description Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democratic Republic of Congo in 1970. In April 2022, several cases were recorded in widespread regions of Africa, the Northern and western hemispheres. The current review spotlights taxonomic classification, clinical presentations during infection, and the pathogenicity of the monkeypox virus in humans. Furthermore, the current review also highlights different diagnostics used for virus detection.
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spelling pubmed-99625272023-02-26 Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review Anwar, Faheem Haider, Fatima Khan, Sarmir Ahmad, Ibrar Ahmed, Naveed Imran, Muhammad Rashid, Summya Ren, Zhi-Guang Khattak, Saadullah Ji, Xin-Ying Life (Basel) Review Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. The first human case of monkeypox was reported throughout the Democratic Republic of Congo in 1970. In April 2022, several cases were recorded in widespread regions of Africa, the Northern and western hemispheres. The current review spotlights taxonomic classification, clinical presentations during infection, and the pathogenicity of the monkeypox virus in humans. Furthermore, the current review also highlights different diagnostics used for virus detection. MDPI 2023-02-14 /pmc/articles/PMC9962527/ /pubmed/36836879 http://dx.doi.org/10.3390/life13020522 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Anwar, Faheem
Haider, Fatima
Khan, Sarmir
Ahmad, Ibrar
Ahmed, Naveed
Imran, Muhammad
Rashid, Summya
Ren, Zhi-Guang
Khattak, Saadullah
Ji, Xin-Ying
Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review
title Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review
title_full Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review
title_fullStr Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review
title_full_unstemmed Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review
title_short Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review
title_sort clinical manifestation, transmission, pathogenesis, and diagnosis of monkeypox virus: a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962527/
https://www.ncbi.nlm.nih.gov/pubmed/36836879
http://dx.doi.org/10.3390/life13020522
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