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The Presence of Testis Determines Aristolochic Acid-Induced Nephrotoxicity in Mice

Aristolochic acid (AA) is notorious for inducing nephrotoxicity, but the influence of sex on AA-induced kidney injury was not clear. This study sought to investigate sex differences in kidney dysfunction and tubular injury induced by AA. Male and female mice were bilaterally orchiectomized and ovari...

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Detalles Bibliográficos
Autores principales: Li, Wei-Long, Padanilam, Babu J., Kim, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962534/
https://www.ncbi.nlm.nih.gov/pubmed/36828432
http://dx.doi.org/10.3390/toxins15020118