Development of a CRISPRi Human Retinal Pigmented Epithelium Model for Functional Study of Age-Related Macular Degeneration Genes

Age-related macular degeneration (AMD) is a blinding disease characterised by dysfunction of the retinal pigmented epithelium (RPE) which culminates in disruption or loss of the neurosensory retina. Genome-wide association studies have identified >60 genetic risk factors for AMD; however, the exp...

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Detalles Bibliográficos
Autores principales: Wang, Jiang-Hui, Urrutia-Cabrera, Daniel, Lees, Jarmon G., Mesa Mora, Santiago, Nguyen, Tu, Hung, Sandy S. C., Hewitt, Alex W., Lim, Shiang Y., Edwards, Thomas L., Wong, Raymond C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962760/
https://www.ncbi.nlm.nih.gov/pubmed/36834828
http://dx.doi.org/10.3390/ijms24043417

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