Combination of EphA2- and Wee1-Targeted Therapies in Endometrial Cancer

EphA2 tyrosine kinase is upregulated in many cancers and correlated with poor survival of patients, including those with endometrial cancer. EphA2-targeted drugs have shown modest clinical benefit. To improve the therapeutic response to such drugs, we performed a high-throughput chemical screen to d...

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Detalles Bibliográficos
Autores principales: Dasari, Santosh K., Joseph, Robiya, Umamaheswaran, Sujanitha, Mangala, Lingegowda S., Bayraktar, Emine, Rodriguez-Aguayo, Cristian, Wu, Yutuan, Nguyen, Nghi, Powell, Reid T., Sobieski, Mary, Liu, Yuan, Chowdhury, Mamur A., Amero, Paola, Stephan, Clifford, Lopez-Berestein, Gabriel, Westin, Shannon N., Sood, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962847/
https://www.ncbi.nlm.nih.gov/pubmed/36835335
http://dx.doi.org/10.3390/ijms24043915

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