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Magnetic Ion Channel Activation (MICA)-Enabled Screening Assay: A Dynamic Platform for Remote Activation of Mechanosensitive Ion Channels

This study reports results of a mechanical platform-based screening assay (MICA) to evaluate the remote activation of mechanosensitive ion channels. Here, we studied ERK pathway activation and the elevation in intracellular Ca(2+) levels in response to the MICA application using the Luciferase assay...

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Detalles Bibliográficos
Autores principales: Unnithan, Afeesh Rajan, Rotherham, Michael, Markides, Hareklea, El Haj, Alicia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962865/
https://www.ncbi.nlm.nih.gov/pubmed/36834776
http://dx.doi.org/10.3390/ijms24043364