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MTHFR c.665C>T and c.1298A>C Polymorphisms in Tailoring Personalized Anti-TNF-α Therapy for Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease with a prevalence of 1%. Currently, RA treatment aims to achieve low disease activity or remission. Failure to achieve this goal causes disease progression with a poor prognosis. When treatment with first-line drugs fails, treatment wit...

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Detalles Bibliográficos
Autores principales: Ravaei, Amin, Pulsatelli, Lia, Assirelli, Elisa, Ciaffi, Jacopo, Meliconi, Riccardo, Salvarani, Carlo, Govoni, Marcello, Rubini, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962934/
https://www.ncbi.nlm.nih.gov/pubmed/36835522
http://dx.doi.org/10.3390/ijms24044110