Cargando…

The Anti-Obesity and Anti-Steatotic Effects of Chrysin in a Rat Model of Obesity Mediated through Modulating the Hepatic AMPK/mTOR/lipogenesis Pathways

Background: Obesity is a complex multifactorial disease characterized by excessive adiposity, and is linked to an increased risk of nonalcoholic fatty liver disease (NAFLD). Flavonoids are natural polyphenolic compounds that exert interesting pharmacological effects as antioxidant, anti-inflammatory...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oriquat, Ghaleb, Masoud, Inas M., Kamel, Maher A., Aboudeya, Hebatallah Mohammed, Bakir, Marwa B., Shaker, Sara A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962978/ https://www.ncbi.nlm.nih.gov/pubmed/36838721 http://dx.doi.org/10.3390/molecules28041734

Ejemplares similares

Effect of short-term high fat diet on resistin levels and expression of autophagy-related genes in the cartilage of male rats
por: Aboudeya, Hebatallah Mohammed, et al.
Publicado: (2022)

Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice
por: Liou, Chian-Jiun, et al.
Publicado: (2020)

Anti-glycation, Carbonyl Trapping and Anti-inflammatory Activities of Chrysin Derivatives
por: Hwang, Seung Hwan, et al.
Publicado: (2018)

Chrysin mitigated obesity by regulating energy intake and expenditure in rats()
por: Pai, Sarayu A., et al.
Publicado: (2019)

β2GPI exerts an anti-obesity effect in female mice by inhibiting lipogenesis and promoting lipolysis
por: Dong, Shangwen, et al.
Publicado: (2017)

Anti-Enterovirus 71 Effects of Chrysin and Its Phosphate Ester
por: Wang, Jianmin, et al.
Publicado: (2014)

The impact of cortisol in steatotic and non‐steatotic liver surgery
por: Cornide‐Petronio, María Eugenia, et al.
Publicado: (2017)

SRC promotes lipogenesis: implications for obesity and breast cancer
por: Lin, Shu-Yong, et al.
Publicado: (2021)

Role of chrysin on expression of insulin signaling molecules
por: Satyanarayana, Kottireddy, et al.
Publicado: (2015)

Anti-Obesity Effects of SPY Fermented with Lactobacillus rhamnosus BST-L.601 via Suppression of Adipogenesis and Lipogenesis in High-Fat Diet-Induced Obese Mice
por: Kang, Taewook, et al.
Publicado: (2023)

Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity
por: Pulido, Marina R., et al.
Publicado: (2011)

IL-1 Signaling in Obesity-Induced Hepatic Lipogenesis and Steatosis
por: Negrin, Kimberly A., et al.
Publicado: (2014)

KHK, PNPLA3 and PPAR as Novel Targets for the Anti-Steatotic Action of Bempedoic Acid
por: Velázquez, Ana Magdalena, et al.
Publicado: (2022)

Anti-steatotic and anti-fibrotic effects of the KCa3.1 channel inhibitor, Senicapoc, in non-alcoholic liver disease
por: Paka, Latha, et al.
Publicado: (2017)

Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects
por: Cho, Jae Min, et al.
Publicado: (2020)

Novel anti-obesity effects of beer hops compound xanthohumol: role of AMPK signaling pathway
por: Samuels, Janaiya S., et al.
Publicado: (2018)

Interaction of Chrysin and Its Main Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide with Serum Albumin
por: Mohos, Violetta, et al.
Publicado: (2018)

Insulin resistance and central obesity determine hepatic steatosis and explain cardiovascular risk in steatotic liver disease
por: Semmler, Georg, et al.
Publicado: (2023)

Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway
por: Lin, Yen-Chung, et al.
Publicado: (2019)

Chrysin Induces Antidiabetic, Antidyslipidemic and Anti-Inflammatory Effects in Athymic Nude Diabetic Mice
por: Ramírez-Espinosa, Juan José, et al.
Publicado: (2017)

Identification of Nifurtimox and Chrysin as Anti-Influenza Virus Agents by Clinical Transcriptome Signature Reversion
por: Xin, Yijing, et al.
Publicado: (2022)

Ameliorative effects of zinc supplementation on cognitive function and hippocampal leptin signaling pathway in obese male and female rats
por: Hafez, Lamia M., et al.
Publicado: (2023)

In Steatotic Cells, ATP-Citrate Lyase mRNA Is Efficiently Translated through a Cap-Independent Mechanism, Contributing to the Stimulation of De Novo Lipogenesis
por: Siculella, Luisa, et al.
Publicado: (2020)

Mitogen Activated Protein Kinases in Steatotic and Non-Steatotic Livers Submitted to Ischemia-Reperfusion
por: Jiménez-Castro, Mónica B., et al.
Publicado: (2019)

Outcomes after Liver Transplantation with Steatotic Grafts: Redefining Acceptable Cutoffs for Steatotic Grafts
por: Da, Ben L, et al.
Publicado: (2022)

Anti-Obesity and Lipid Lowering Activity of Bauhiniastatin-1 is Mediated Through PPAR-γ/AMPK Expressions in Diet-Induced Obese Rat Model
por: Karunakaran, Reddy Sankaran, et al.
Publicado: (2021)

Triglyceride Mobilization from Lipid Droplets Sustains the Anti-Steatotic Action of Iodothyronines in Cultured Rat Hepatocytes
por: Grasselli, Elena, et al.
Publicado: (2016)

Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis
por: Zhao, Xu-Yun, et al.
Publicado: (2018)

Hepatic Gene Expression Profiles Differentiate Steatotic and Non-steatotic Grafts in Liver Transplant Recipients
por: Šeda, Ondrej, et al.
Publicado: (2019)

The Role of Neuregulin-1 in Steatotic and Non-Steatotic Liver Transplantation from Brain-Dead Donors
por: Micó-Carnero, Marc, et al.
Publicado: (2022)

Anti-obesity effect of Solidago virgaurea var. g igantea extract through regulation of adipogenesis and lipogenesis pathways in high-fat diet-induced obese mice (C57BL/6N)
por: Wang, Zhiqiang, et al.
Publicado: (2017)

Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways
por: Guo, Liemei, et al.
Publicado: (2020)

Chrysin Induces Apoptosis and Autophagy in Human Melanoma Cells via the mTOR/S6K Pathway
por: Lee, Jae-Han, et al.
Publicado: (2022)

The Role of GLP1 in Rat Steatotic and Non-Steatotic Liver Transplantation from Cardiocirculatory Death Donors
por: Avalos-de León, Cindy G., et al.
Publicado: (2019)

The Antimicrobial, Antioxidative, and Anti-Inflammatory Effects of Polycaprolactone/Gelatin Scaffolds Containing Chrysin for Regenerative Endodontic Purposes
por: Alipour, Mahdieh, et al.
Publicado: (2021)

Antioxidative and Anti-Inflammatory Activities of Chrysin and Naringenin in a Drug-Induced Bone Loss Model in Rats
por: Oršolić, Nada, et al.
Publicado: (2022)

Chrysin targets myeloid‐derived suppressor cells and enhances tumour response to anti‐PD‐1 immunotherapy
por: Li, Yinan, et al.
Publicado: (2022)

3,5-T2-an Endogenous Thyroid Hormone Metabolite as Promising Lead Substance in Anti-Steatotic Drug Development?
por: Sane, Rajas, et al.
Publicado: (2022)

First Evidence of Anti-Steatotic Action of Macrotympanain A1, an Amphibian Skin Peptide from Odorrana macrotympana
por: Demori, Ilaria, et al.
Publicado: (2022)

Anti-Steatotic Effects of Chlorella vulgaris, Nannochloropsis gaditana and Gracilaria vermiculophylla Algae Extracts in AML-12 Hepatocytes
por: González-Arceo, Maitane, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1rnhu58ckmdjs1nqnh8jofg8so