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Quantitative analysis of sterol-modulated monomer–dimer equilibrium of the β(1)-adrenergic receptor by DEER spectroscopy

G protein-coupled receptors (GPCR) activate numerous intracellular signaling pathways. The oligomerization properties of GPCRs, and hence their cellular functions, may be modulated by various components within the cell membrane (such as the presence of cholesterol). Modulation may occur directly via...

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Detalles Bibliográficos
Autores principales:	Kubatova, Nina, Schmidt, Thomas, Schwieters, Charles D., Clore, G. Marius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963004/ https://www.ncbi.nlm.nih.gov/pubmed/36745787 http://dx.doi.org/10.1073/pnas.2221036120

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