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Virtual Screening of Hepatitis B Virus Pre-Genomic RNA as a Novel Therapeutic Target

The global burden imposed by hepatitis B virus (HBV) infection necessitates the discovery and design of novel antiviral drugs to complement existing treatments. One attractive and underexploited therapeutic target is ε, an ~85-nucleotide (nt) cis-acting regulatory stem-loop RNA located at the 3′- an...

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Detalles Bibliográficos
Autores principales: Olenginski, Lukasz T., Kasprzak, Wojciech K., Attionu, Solomon K., Shapiro, Bruce A., Dayie, Theodore K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963113/
https://www.ncbi.nlm.nih.gov/pubmed/36838792
http://dx.doi.org/10.3390/molecules28041803