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Age Stratification and Stroke Severity in the Telestroke Network

Background. Age is one of the most important risk factors for stroke, and an estimated 75% of strokes occur in people 65 years old and above. Adults > 75 years of age experience more hospitalizations and higher mortality. In this study, we aimed to investigate how age and various clinical risk fa...

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Autores principales: Simmons, Cassie A., Poupore, Nicolas, Nathaniel, Thomas I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963120/
https://www.ncbi.nlm.nih.gov/pubmed/36836054
http://dx.doi.org/10.3390/jcm12041519
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author Simmons, Cassie A.
Poupore, Nicolas
Nathaniel, Thomas I.
author_facet Simmons, Cassie A.
Poupore, Nicolas
Nathaniel, Thomas I.
author_sort Simmons, Cassie A.
collection PubMed
description Background. Age is one of the most important risk factors for stroke, and an estimated 75% of strokes occur in people 65 years old and above. Adults > 75 years of age experience more hospitalizations and higher mortality. In this study, we aimed to investigate how age and various clinical risk factors affect acute ischemic stroke (AIS) severity in two age categories. Methods. This retrospective data analysis study was conducted using data collected from the PRISMA Health Stroke Registry between June 2010 and July 2016. Baseline clinical and demographic data were analyzed for 65–74-year-old patients and those ≥ 75 years of age. This study aimed to investigate risk factors associated with stroke severity in these two age categories of AIS patients treated in telestroke settings. Results. An adjusted multivariate analysis showed that the acute ischemic stroke (AIS) population of 65–74-year-old patients experiencing heart failure (odds ratio (OR) = 4.398, 95% CI = 3.912–494.613, p = 0.002) and elevated high-density lipoprotein (HDL) levels (OR = 1.066, 95% CI = 1.009–1.126, p = 0.024) trended towards worsening neurological function, while patients experiencing obesity (OR = 0.177, 95% CI = 0.041–0.760, p = 0.020) exhibited improved neurological functions. For the patients ≥ 75 years of age, direct admission (OR = 0.270, 95% CI = 0.085–0.856, p = 0.026) was associated with improved functions. Conclusions. Heart failure and elevated HDL levels were significantly associated with worsening neurologic functions in patients aged 65–74. Obese patients and individuals ≥ 75 years of age who were directly admitted were most likely to exhibit improving neurological functions.
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spelling pubmed-99631202023-02-26 Age Stratification and Stroke Severity in the Telestroke Network Simmons, Cassie A. Poupore, Nicolas Nathaniel, Thomas I. J Clin Med Article Background. Age is one of the most important risk factors for stroke, and an estimated 75% of strokes occur in people 65 years old and above. Adults > 75 years of age experience more hospitalizations and higher mortality. In this study, we aimed to investigate how age and various clinical risk factors affect acute ischemic stroke (AIS) severity in two age categories. Methods. This retrospective data analysis study was conducted using data collected from the PRISMA Health Stroke Registry between June 2010 and July 2016. Baseline clinical and demographic data were analyzed for 65–74-year-old patients and those ≥ 75 years of age. This study aimed to investigate risk factors associated with stroke severity in these two age categories of AIS patients treated in telestroke settings. Results. An adjusted multivariate analysis showed that the acute ischemic stroke (AIS) population of 65–74-year-old patients experiencing heart failure (odds ratio (OR) = 4.398, 95% CI = 3.912–494.613, p = 0.002) and elevated high-density lipoprotein (HDL) levels (OR = 1.066, 95% CI = 1.009–1.126, p = 0.024) trended towards worsening neurological function, while patients experiencing obesity (OR = 0.177, 95% CI = 0.041–0.760, p = 0.020) exhibited improved neurological functions. For the patients ≥ 75 years of age, direct admission (OR = 0.270, 95% CI = 0.085–0.856, p = 0.026) was associated with improved functions. Conclusions. Heart failure and elevated HDL levels were significantly associated with worsening neurologic functions in patients aged 65–74. Obese patients and individuals ≥ 75 years of age who were directly admitted were most likely to exhibit improving neurological functions. MDPI 2023-02-14 /pmc/articles/PMC9963120/ /pubmed/36836054 http://dx.doi.org/10.3390/jcm12041519 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Simmons, Cassie A.
Poupore, Nicolas
Nathaniel, Thomas I.
Age Stratification and Stroke Severity in the Telestroke Network
title Age Stratification and Stroke Severity in the Telestroke Network
title_full Age Stratification and Stroke Severity in the Telestroke Network
title_fullStr Age Stratification and Stroke Severity in the Telestroke Network
title_full_unstemmed Age Stratification and Stroke Severity in the Telestroke Network
title_short Age Stratification and Stroke Severity in the Telestroke Network
title_sort age stratification and stroke severity in the telestroke network
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963120/
https://www.ncbi.nlm.nih.gov/pubmed/36836054
http://dx.doi.org/10.3390/jcm12041519
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