Synthesis and Biological Evaluation of Octahydroquinazolinones as Phospholipase A2, and Protease Inhibitors: Experimental and Theoretical Exploration

Phospholipase A2 (PLA2) promotes inflammation via lipid mediators and releases arachidonic acid (AA), and these enzymes have been found to be elevated in a variety of diseases, including rheumatoid arthritis, sepsis, and atherosclerosis. The mobilization of AA by PLA2 and subsequent synthesis of pro...

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Detalles Bibliográficos
Autores principales: Bakht, Md. Afroz, Pooventhiran, Thangaiyan, Thomas, Renjith, Kamal, Mehnaz, Din, Israf Ud, Rehman, Najeeb Ur, Ali, Imtiaz, Ajmal, Noushin, Ahsan, Mohamed Jawed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963251/
https://www.ncbi.nlm.nih.gov/pubmed/36838935
http://dx.doi.org/10.3390/molecules28041944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963251/
https://www.ncbi.nlm.nih.gov/pubmed/36838935
http://dx.doi.org/10.3390/molecules28041944

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