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How Radiomics Can Improve Breast Cancer Diagnosis and Treatment

Recent technological advances in the field of artificial intelligence hold promise in addressing medical challenges in breast cancer care, such as early diagnosis, cancer subtype determination and molecular profiling, prediction of lymph node metastases, and prognostication of treatment response and...

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Autores principales: Pesapane, Filippo, De Marco, Paolo, Rapino, Anna, Lombardo, Eleonora, Nicosia, Luca, Tantrige, Priyan, Rotili, Anna, Bozzini, Anna Carla, Penco, Silvia, Dominelli, Valeria, Trentin, Chiara, Ferrari, Federica, Farina, Mariagiorgia, Meneghetti, Lorenza, Latronico, Antuono, Abbate, Francesca, Origgi, Daniela, Carrafiello, Gianpaolo, Cassano, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963325/
https://www.ncbi.nlm.nih.gov/pubmed/36835908
http://dx.doi.org/10.3390/jcm12041372
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author Pesapane, Filippo
De Marco, Paolo
Rapino, Anna
Lombardo, Eleonora
Nicosia, Luca
Tantrige, Priyan
Rotili, Anna
Bozzini, Anna Carla
Penco, Silvia
Dominelli, Valeria
Trentin, Chiara
Ferrari, Federica
Farina, Mariagiorgia
Meneghetti, Lorenza
Latronico, Antuono
Abbate, Francesca
Origgi, Daniela
Carrafiello, Gianpaolo
Cassano, Enrico
author_facet Pesapane, Filippo
De Marco, Paolo
Rapino, Anna
Lombardo, Eleonora
Nicosia, Luca
Tantrige, Priyan
Rotili, Anna
Bozzini, Anna Carla
Penco, Silvia
Dominelli, Valeria
Trentin, Chiara
Ferrari, Federica
Farina, Mariagiorgia
Meneghetti, Lorenza
Latronico, Antuono
Abbate, Francesca
Origgi, Daniela
Carrafiello, Gianpaolo
Cassano, Enrico
author_sort Pesapane, Filippo
collection PubMed
description Recent technological advances in the field of artificial intelligence hold promise in addressing medical challenges in breast cancer care, such as early diagnosis, cancer subtype determination and molecular profiling, prediction of lymph node metastases, and prognostication of treatment response and probability of recurrence. Radiomics is a quantitative approach to medical imaging, which aims to enhance the existing data available to clinicians by means of advanced mathematical analysis using artificial intelligence. Various published studies from different fields in imaging have highlighted the potential of radiomics to enhance clinical decision making. In this review, we describe the evolution of AI in breast imaging and its frontiers, focusing on handcrafted and deep learning radiomics. We present a typical workflow of a radiomics analysis and a practical “how-to” guide. Finally, we summarize the methodology and implementation of radiomics in breast cancer, based on the most recent scientific literature to help researchers and clinicians gain fundamental knowledge of this emerging technology. Alongside this, we discuss the current limitations of radiomics and challenges of integration into clinical practice with conceptual consistency, data curation, technical reproducibility, adequate accuracy, and clinical translation. The incorporation of radiomics with clinical, histopathological, and genomic information will enable physicians to move forward to a higher level of personalized management of patients with breast cancer.
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spelling pubmed-99633252023-02-26 How Radiomics Can Improve Breast Cancer Diagnosis and Treatment Pesapane, Filippo De Marco, Paolo Rapino, Anna Lombardo, Eleonora Nicosia, Luca Tantrige, Priyan Rotili, Anna Bozzini, Anna Carla Penco, Silvia Dominelli, Valeria Trentin, Chiara Ferrari, Federica Farina, Mariagiorgia Meneghetti, Lorenza Latronico, Antuono Abbate, Francesca Origgi, Daniela Carrafiello, Gianpaolo Cassano, Enrico J Clin Med Review Recent technological advances in the field of artificial intelligence hold promise in addressing medical challenges in breast cancer care, such as early diagnosis, cancer subtype determination and molecular profiling, prediction of lymph node metastases, and prognostication of treatment response and probability of recurrence. Radiomics is a quantitative approach to medical imaging, which aims to enhance the existing data available to clinicians by means of advanced mathematical analysis using artificial intelligence. Various published studies from different fields in imaging have highlighted the potential of radiomics to enhance clinical decision making. In this review, we describe the evolution of AI in breast imaging and its frontiers, focusing on handcrafted and deep learning radiomics. We present a typical workflow of a radiomics analysis and a practical “how-to” guide. Finally, we summarize the methodology and implementation of radiomics in breast cancer, based on the most recent scientific literature to help researchers and clinicians gain fundamental knowledge of this emerging technology. Alongside this, we discuss the current limitations of radiomics and challenges of integration into clinical practice with conceptual consistency, data curation, technical reproducibility, adequate accuracy, and clinical translation. The incorporation of radiomics with clinical, histopathological, and genomic information will enable physicians to move forward to a higher level of personalized management of patients with breast cancer. MDPI 2023-02-09 /pmc/articles/PMC9963325/ /pubmed/36835908 http://dx.doi.org/10.3390/jcm12041372 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pesapane, Filippo
De Marco, Paolo
Rapino, Anna
Lombardo, Eleonora
Nicosia, Luca
Tantrige, Priyan
Rotili, Anna
Bozzini, Anna Carla
Penco, Silvia
Dominelli, Valeria
Trentin, Chiara
Ferrari, Federica
Farina, Mariagiorgia
Meneghetti, Lorenza
Latronico, Antuono
Abbate, Francesca
Origgi, Daniela
Carrafiello, Gianpaolo
Cassano, Enrico
How Radiomics Can Improve Breast Cancer Diagnosis and Treatment
title How Radiomics Can Improve Breast Cancer Diagnosis and Treatment
title_full How Radiomics Can Improve Breast Cancer Diagnosis and Treatment
title_fullStr How Radiomics Can Improve Breast Cancer Diagnosis and Treatment
title_full_unstemmed How Radiomics Can Improve Breast Cancer Diagnosis and Treatment
title_short How Radiomics Can Improve Breast Cancer Diagnosis and Treatment
title_sort how radiomics can improve breast cancer diagnosis and treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963325/
https://www.ncbi.nlm.nih.gov/pubmed/36835908
http://dx.doi.org/10.3390/jcm12041372
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