Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction

Non-coding RNAs have been excavated as important cardiac function modulators and linked to heart diseases. Significant advances have been obtained in illuminating the effects of microRNAs and long non-coding RNAs. Nevertheless, the characteristics of circular RNAs are rarely mined. Circular RNAs (ci...

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Detalles Bibliográficos
Autores principales: Li, Jialei, Han, Yu, Wang, Shuang, Wu, Xiaolei, Cao, Jimin, Sun, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963350/
https://www.ncbi.nlm.nih.gov/pubmed/36835653
http://dx.doi.org/10.3390/ijms24044233
Descripción
Sumario:Non-coding RNAs have been excavated as important cardiac function modulators and linked to heart diseases. Significant advances have been obtained in illuminating the effects of microRNAs and long non-coding RNAs. Nevertheless, the characteristics of circular RNAs are rarely mined. Circular RNAs (circRNAs) are widely believed to participate in cardiac pathologic processes, especially in myocardial infarction. In this review, we round up the biogenesis of circRNAs, briefly describe their biological functions, and summarize the latest literature on multifarious circRNAs related to new therapies and biomarkers for myocardial infarction.

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