Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction

Non-coding RNAs have been excavated as important cardiac function modulators and linked to heart diseases. Significant advances have been obtained in illuminating the effects of microRNAs and long non-coding RNAs. Nevertheless, the characteristics of circular RNAs are rarely mined. Circular RNAs (ci...

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Detalles Bibliográficos
Autores principales: Li, Jialei, Han, Yu, Wang, Shuang, Wu, Xiaolei, Cao, Jimin, Sun, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963350/
https://www.ncbi.nlm.nih.gov/pubmed/36835653
http://dx.doi.org/10.3390/ijms24044233
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author Li, Jialei
Han, Yu
Wang, Shuang
Wu, Xiaolei
Cao, Jimin
Sun, Teng
author_facet Li, Jialei
Han, Yu
Wang, Shuang
Wu, Xiaolei
Cao, Jimin
Sun, Teng
author_sort Li, Jialei
collection PubMed
description Non-coding RNAs have been excavated as important cardiac function modulators and linked to heart diseases. Significant advances have been obtained in illuminating the effects of microRNAs and long non-coding RNAs. Nevertheless, the characteristics of circular RNAs are rarely mined. Circular RNAs (circRNAs) are widely believed to participate in cardiac pathologic processes, especially in myocardial infarction. In this review, we round up the biogenesis of circRNAs, briefly describe their biological functions, and summarize the latest literature on multifarious circRNAs related to new therapies and biomarkers for myocardial infarction.
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spelling pubmed-99633502023-02-26 Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction Li, Jialei Han, Yu Wang, Shuang Wu, Xiaolei Cao, Jimin Sun, Teng Int J Mol Sci Review Non-coding RNAs have been excavated as important cardiac function modulators and linked to heart diseases. Significant advances have been obtained in illuminating the effects of microRNAs and long non-coding RNAs. Nevertheless, the characteristics of circular RNAs are rarely mined. Circular RNAs (circRNAs) are widely believed to participate in cardiac pathologic processes, especially in myocardial infarction. In this review, we round up the biogenesis of circRNAs, briefly describe their biological functions, and summarize the latest literature on multifarious circRNAs related to new therapies and biomarkers for myocardial infarction. MDPI 2023-02-20 /pmc/articles/PMC9963350/ /pubmed/36835653 http://dx.doi.org/10.3390/ijms24044233 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Li, Jialei
Han, Yu
Wang, Shuang
Wu, Xiaolei
Cao, Jimin
Sun, Teng
Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction
title Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction
title_full Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction
title_fullStr Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction
title_full_unstemmed Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction
title_short Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction
title_sort circular rnas: biogenesis, biological functions, and roles in myocardial infarction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963350/
https://www.ncbi.nlm.nih.gov/pubmed/36835653
http://dx.doi.org/10.3390/ijms24044233
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