Cargando…
Corneal Optical Densitometry in the Evaluation of 2-Year Graft Function Following Endothelial Keratoplasty
This study aimed to assess clinical application of the Scheimpflug corneal tomography for objective evaluation of corneal optical density in eyes undergoing Descemet’s stripping endothelial keratoplasty (DSEK). In this prospective study, 39 pseudophakic eyes with bullous keratopathy were enrolled. A...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963363/ https://www.ncbi.nlm.nih.gov/pubmed/36836087 http://dx.doi.org/10.3390/jcm12041552 |
_version_ | 1784896234533683200 |
---|---|
author | Piotrowiak-Słupska, Ilona Kałużny, Bartłomiej J. Malukiewicz, Grażyna |
author_facet | Piotrowiak-Słupska, Ilona Kałużny, Bartłomiej J. Malukiewicz, Grażyna |
author_sort | Piotrowiak-Słupska, Ilona |
collection | PubMed |
description | This study aimed to assess clinical application of the Scheimpflug corneal tomography for objective evaluation of corneal optical density in eyes undergoing Descemet’s stripping endothelial keratoplasty (DSEK). In this prospective study, 39 pseudophakic eyes with bullous keratopathy were enrolled. All eyes underwent primary DSEK. Ophthalmic examination included best corrected visual acuity (BCVA) measurement, biomicroscopy, Scheimpflug tomography, pachymetry, and endothelial cell count. All measurements were taken preoperatively and within a 2-year follow-up period. Gradual BCVA improvement was observed in all patients. After two years, the mean and median BCVA values were 0.18 logMAR. A decrease in central corneal thickness was noted only during the first 3 months postoperatively and was followed by a gradual increase. Corneal densitometry decreased constantly and most significantly in the first 3 months postoperatively. The consecutive decrease in endothelial cell count of the transplanted cornea was most significant during the first 6 months postoperatively. Six months postoperatively, the strongest correlation (Spearman’s r = −0.41) with BCVA was found for densitometry. This tendency was maintained throughout the entire follow-up period. Corneal densitometry is applicable for objective monitoring of early and late outcomes of endothelial keratoplasty, showing a higher correlation with visual acuity than pachymetry and endothelial cell density. |
format | Online Article Text |
id | pubmed-9963363 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99633632023-02-26 Corneal Optical Densitometry in the Evaluation of 2-Year Graft Function Following Endothelial Keratoplasty Piotrowiak-Słupska, Ilona Kałużny, Bartłomiej J. Malukiewicz, Grażyna J Clin Med Article This study aimed to assess clinical application of the Scheimpflug corneal tomography for objective evaluation of corneal optical density in eyes undergoing Descemet’s stripping endothelial keratoplasty (DSEK). In this prospective study, 39 pseudophakic eyes with bullous keratopathy were enrolled. All eyes underwent primary DSEK. Ophthalmic examination included best corrected visual acuity (BCVA) measurement, biomicroscopy, Scheimpflug tomography, pachymetry, and endothelial cell count. All measurements were taken preoperatively and within a 2-year follow-up period. Gradual BCVA improvement was observed in all patients. After two years, the mean and median BCVA values were 0.18 logMAR. A decrease in central corneal thickness was noted only during the first 3 months postoperatively and was followed by a gradual increase. Corneal densitometry decreased constantly and most significantly in the first 3 months postoperatively. The consecutive decrease in endothelial cell count of the transplanted cornea was most significant during the first 6 months postoperatively. Six months postoperatively, the strongest correlation (Spearman’s r = −0.41) with BCVA was found for densitometry. This tendency was maintained throughout the entire follow-up period. Corneal densitometry is applicable for objective monitoring of early and late outcomes of endothelial keratoplasty, showing a higher correlation with visual acuity than pachymetry and endothelial cell density. MDPI 2023-02-16 /pmc/articles/PMC9963363/ /pubmed/36836087 http://dx.doi.org/10.3390/jcm12041552 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Piotrowiak-Słupska, Ilona Kałużny, Bartłomiej J. Malukiewicz, Grażyna Corneal Optical Densitometry in the Evaluation of 2-Year Graft Function Following Endothelial Keratoplasty |
title | Corneal Optical Densitometry in the Evaluation of 2-Year Graft Function Following Endothelial Keratoplasty |
title_full | Corneal Optical Densitometry in the Evaluation of 2-Year Graft Function Following Endothelial Keratoplasty |
title_fullStr | Corneal Optical Densitometry in the Evaluation of 2-Year Graft Function Following Endothelial Keratoplasty |
title_full_unstemmed | Corneal Optical Densitometry in the Evaluation of 2-Year Graft Function Following Endothelial Keratoplasty |
title_short | Corneal Optical Densitometry in the Evaluation of 2-Year Graft Function Following Endothelial Keratoplasty |
title_sort | corneal optical densitometry in the evaluation of 2-year graft function following endothelial keratoplasty |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963363/ https://www.ncbi.nlm.nih.gov/pubmed/36836087 http://dx.doi.org/10.3390/jcm12041552 |
work_keys_str_mv | AT piotrowiaksłupskailona cornealopticaldensitometryintheevaluationof2yeargraftfunctionfollowingendothelialkeratoplasty AT kałuznybartłomiejj cornealopticaldensitometryintheevaluationof2yeargraftfunctionfollowingendothelialkeratoplasty AT malukiewiczgrazyna cornealopticaldensitometryintheevaluationof2yeargraftfunctionfollowingendothelialkeratoplasty |