Cargando…

VDAC1 Knockout Affects Mitochondrial Oxygen Consumption Triggering a Rearrangement of ETC by Impacting on Complex I Activity

Voltage-Dependent Anion-selective Channel isoform 1 (VDAC1) is the most abundant isoform of the outer mitochondrial membrane (OMM) porins and the principal gate for ions and metabolites to and from the organelle. VDAC1 is also involved in a number of additional functions, such as the regulation of a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Magrì, Andrea, Cubisino, Salvatore Antonio Maria, Battiato, Giuseppe, Lipari, Cristiana Lucia Rita, Conti Nibali, Stefano, Saab, Miriam Wissam, Pittalà, Alessandra, Amorini, Angela Maria, De Pinto, Vito, Messina, Angela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963415/ https://www.ncbi.nlm.nih.gov/pubmed/36835102 http://dx.doi.org/10.3390/ijms24043687

Ejemplares similares

Specific Post-Translational Modifications of VDAC3 in ALS-SOD1 Model Cells Identified by High-Resolution Mass Spectrometry
por: Pittalà, Maria Gaetana Giovanna, et al.
Publicado: (2022)

Voltage Dependent Anion Channel 3 (VDAC3) protects mitochondria from oxidative stress
por: Reina, Simona, et al.
Publicado: (2022)

VDACs Post-Translational Modifications Discovery by Mass Spectrometry: Impact on Their Hub Function
por: Pittalà, Maria Gaetana Giovanna, et al.
Publicado: (2021)

Recombinant yeast VDAC2: a comparison of electrophysiological features with the native form
por: Magrì, Andrea, et al.
Publicado: (2019)

α-Synuclein A53T Promotes Mitochondrial Proton Gradient Dissipation and Depletion of the Organelle Respiratory Reserve in a Neuroblastoma Cell Line
por: Risiglione, Pierpaolo, et al.
Publicado: (2022)

Post-Translational Modification Analysis of VDAC1 in ALS-SOD1 Model Cells Reveals Specific Asparagine and Glutamine Deamidation
por: Pittalà, Maria Gaetana Giovanna, et al.
Publicado: (2020)

Cysteine Oxidations in Mitochondrial Membrane Proteins: The Case of VDAC Isoforms in Mammals
por: Reina, Simona, et al.
Publicado: (2020)

Cell-free electrophysiology of human VDACs incorporated into nanodiscs: An improved method
por: Conti Nibali, Stefano, et al.
Publicado: (2021)

Alpha-Synuclein and Mitochondrial Dysfunction in Parkinson’s Disease: The Emerging Role of VDAC
por: Risiglione, Pierpaolo, et al.
Publicado: (2021)

Editorial: VDAC Structure and Function: An Up-to-Date View
por: De Pinto, Vito, et al.
Publicado: (2022)

VDAC as a Cellular Hub: Docking Molecules and Interactions
por: Kmita, Hanna, et al.
Publicado: (2023)

Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia
por: Pappalardo, Xena Giada, et al.
Publicado: (2023)

Is the Secret of VDAC Isoforms in Their Gene Regulation? Characterization of Human VDAC Genes Expression Profile, Promoter Activity, and Transcriptional Regulators
por: Zinghirino, Federica, et al.
Publicado: (2020)

VDAC Genes Expression and Regulation in Mammals
por: Zinghirino, Federica, et al.
Publicado: (2021)

Traumatic Brain Injury Alters Cerebral Concentrations and Redox States of Coenzymes Q(9) and Q(10) in the Rat
por: Lazzarino, Giacomo, et al.
Publicado: (2023)

A VDAC1-Derived N-Terminal Peptide Inhibits Mutant SOD1-VDAC1 Interactions and Toxicity in the SOD1 Model of ALS
por: Shteinfer-Kuzmine, Anna, et al.
Publicado: (2019)

Hexokinase I N-terminal based peptide prevents the VDAC1-SOD1 G93A interaction and re-establishes ALS cell viability
por: Magrì, Andrea, et al.
Publicado: (2016)

VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis
por: Magrì, Andrea, et al.
Publicado: (2018)

VDAC1 in the diseased myocardium and the effect of VDAC1-interacting compound on atrial fibrosis induced by hyperaldosteronism
por: Klapper-Goldstein, Hadar, et al.
Publicado: (2020)

VDAC3 As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology
por: Reina, Simona, et al.
Publicado: (2016)

VDAC1 and the TSPO: Expression, Interactions, and Associated Functions in Health and Disease States
por: Shoshan-Barmatz, Varda, et al.
Publicado: (2019)

VDAC3 as a sensor of oxidative state of the intermembrane space of mitochondria: the putative role of cysteine residue modifications
por: Reina, Simona, et al.
Publicado: (2016)

The Voltage-Dependent Anion Selective Channel 1 (VDAC1) Topography in the Mitochondrial Outer Membrane as Detected in Intact Cell
por: Tomasello, Marianna F., et al.
Publicado: (2013)

Metabolic Signature of Energy Metabolism Alterations and Excess Nitric Oxide Production in Culture Media Correlate with Low Human Embryo Quality and Unsuccessful Pregnancy
por: Pallisco, Romina, et al.
Publicado: (2023)

Characterization of Carnosine Effect on Human Microglial Cells under Basal Conditions
por: Caruso, Giuseppe, et al.
Publicado: (2023)

ERK1/2-dependent TSPO overactivation associates with the loss of mitophagy and mitochondrial respiration in ALS
por: Magrì, Andrea, et al.
Publicado: (2023)

Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide
por: Pittala, Srinivas, et al.
Publicado: (2018)

A High Resolution Mass Spectrometry Study Reveals the Potential of Disulfide Formation in Human Mitochondrial Voltage-Dependent Anion Selective Channel Isoforms (hVDACs)
por: Pittalà, Maria G. G., et al.
Publicado: (2020)

Voltage-Dependent Anion Selective Channel Isoforms in Yeast: Expression, Structure, and Functions
por: Di Rosa, Maria Carmela, et al.
Publicado: (2021)

Consumption; Its Treatment, Etc.
por: Salisbury, James H.
Publicado: (1879)

Consumption: Its Nature, Etc.
Publicado: (1886)

A lower affinity to cytosolic proteins reveals VDAC3 isoform-specific role in mitochondrial biology
por: Queralt-Martín, María, et al.
Publicado: (2020)

The VDAC1-based R-Tf-D-LP4 Peptide as a Potential Treatment for Diabetes Mellitus
por: Pittala, Srinivas, et al.
Publicado: (2020)

Rewiring of Cancer Cell Metabolism by Mitochondrial VDAC1 Depletion Results in Time-Dependent Tumor Reprogramming: Glioblastoma as a Proof of Concept
por: Arif, Tasleem, et al.
Publicado: (2019)

Antioxidant-Based Therapies in Male Infertility: Do We Have Sufficient Evidence Supporting Their Effectiveness?
por: Amorini, Angela Maria, et al.
Publicado: (2021)

High-Resolution Respirometry Reveals MPP(+) Mitochondrial Toxicity Mechanism in a Cellular Model of Parkinson’s Disease
por: Risiglione, Pierpaolo, et al.
Publicado: (2020)

Ferro-Phosphas Calcis in Pulmonary Consumption, Etc.
por: Ramsay, H. A.
Publicado: (1853)

Altered Follicular Fluid Metabolic Pattern Correlates with Female Infertility and Outcome Measures of In Vitro Fertilization
por: Lazzarino, Giacomo, et al.
Publicado: (2021)

VDAC—A Primal Perspective
por: Mannella, Carmen A.
Publicado: (2021)

Renaissance of VDAC: New Insights on a Protein Family at the Interface between Mitochondria and Cytosol
por: De Pinto, Vito
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o8rrchu78j4koqhgs7f17ilsed