Cargando…
High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study
Over 250 million infants in low and middle-income countries do not fulfill their neurodevelopment potential. In this study, we assessed the incidence and risk factors for neurodevelopmental delay (NDD) among children born following obstructed labor in Eastern Uganda. Between October 2021 and April 2...
Autores principales: | , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963417/ https://www.ncbi.nlm.nih.gov/pubmed/36834165 http://dx.doi.org/10.3390/ijerph20043470 |
_version_ | 1784896248541609984 |
---|---|
author | Chebet, Martin Musaba, Milton W. Mukunya, David Makoko, Brian Napyo, Agnes Nantale, Ritah Auma, Proscovia Atim, Ketty Nahurira, Doreck Lee, Seungwon Okello, Dedan Ssegawa, Lawrence Bromley, Kieran Burgoine, Kathy Ndeezi, Grace Tumwine, James K. Wandabwa, Julius Kiguli, Sarah |
author_facet | Chebet, Martin Musaba, Milton W. Mukunya, David Makoko, Brian Napyo, Agnes Nantale, Ritah Auma, Proscovia Atim, Ketty Nahurira, Doreck Lee, Seungwon Okello, Dedan Ssegawa, Lawrence Bromley, Kieran Burgoine, Kathy Ndeezi, Grace Tumwine, James K. Wandabwa, Julius Kiguli, Sarah |
author_sort | Chebet, Martin |
collection | PubMed |
description | Over 250 million infants in low and middle-income countries do not fulfill their neurodevelopment potential. In this study, we assessed the incidence and risk factors for neurodevelopmental delay (NDD) among children born following obstructed labor in Eastern Uganda. Between October 2021 and April 2022, we conducted a cohort study of 155 children (aged 25 to 44 months), born at term and assessed their neurodevelopment using the Malawi Developmental Assessment Tool. We assessed the gross motor, fine motor, language and social domains of neurodevelopment. The incidence of neurodevelopmental delay by 25 to 44 months was 67.7% (105/155) (95% CI: 59.8–75.0). Children belonging to the poorest wealth quintile had 83% higher risk of NDD compared to children belonging to the richest quintile (ARR (Adjusted Risk Ratio): 1.83; 95% CI (Confidence Interval): [1.13, 2.94]). Children fed the recommended meal diversity had 25% lower risk of neurodevelopmental delay compared to children who did not (ARR: 0.75; 95% CI: [0.60, 0.94]). Children who were exclusively breastfed for the first 6 months had 27% lower risk of neurodevelopmental delay compared to children who were not (ARR: 0.73; 95% CI: [0.56, 0.96]). We recommend that infants born following obstructed labor undergo neurodevelopmental delay screening. |
format | Online Article Text |
id | pubmed-9963417 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99634172023-02-26 High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study Chebet, Martin Musaba, Milton W. Mukunya, David Makoko, Brian Napyo, Agnes Nantale, Ritah Auma, Proscovia Atim, Ketty Nahurira, Doreck Lee, Seungwon Okello, Dedan Ssegawa, Lawrence Bromley, Kieran Burgoine, Kathy Ndeezi, Grace Tumwine, James K. Wandabwa, Julius Kiguli, Sarah Int J Environ Res Public Health Article Over 250 million infants in low and middle-income countries do not fulfill their neurodevelopment potential. In this study, we assessed the incidence and risk factors for neurodevelopmental delay (NDD) among children born following obstructed labor in Eastern Uganda. Between October 2021 and April 2022, we conducted a cohort study of 155 children (aged 25 to 44 months), born at term and assessed their neurodevelopment using the Malawi Developmental Assessment Tool. We assessed the gross motor, fine motor, language and social domains of neurodevelopment. The incidence of neurodevelopmental delay by 25 to 44 months was 67.7% (105/155) (95% CI: 59.8–75.0). Children belonging to the poorest wealth quintile had 83% higher risk of NDD compared to children belonging to the richest quintile (ARR (Adjusted Risk Ratio): 1.83; 95% CI (Confidence Interval): [1.13, 2.94]). Children fed the recommended meal diversity had 25% lower risk of neurodevelopmental delay compared to children who did not (ARR: 0.75; 95% CI: [0.60, 0.94]). Children who were exclusively breastfed for the first 6 months had 27% lower risk of neurodevelopmental delay compared to children who were not (ARR: 0.73; 95% CI: [0.56, 0.96]). We recommend that infants born following obstructed labor undergo neurodevelopmental delay screening. MDPI 2023-02-16 /pmc/articles/PMC9963417/ /pubmed/36834165 http://dx.doi.org/10.3390/ijerph20043470 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chebet, Martin Musaba, Milton W. Mukunya, David Makoko, Brian Napyo, Agnes Nantale, Ritah Auma, Proscovia Atim, Ketty Nahurira, Doreck Lee, Seungwon Okello, Dedan Ssegawa, Lawrence Bromley, Kieran Burgoine, Kathy Ndeezi, Grace Tumwine, James K. Wandabwa, Julius Kiguli, Sarah High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study |
title | High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study |
title_full | High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study |
title_fullStr | High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study |
title_full_unstemmed | High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study |
title_short | High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study |
title_sort | high burden of neurodevelopmental delay among children born to women with obstructed labour in eastern uganda: a cohort study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963417/ https://www.ncbi.nlm.nih.gov/pubmed/36834165 http://dx.doi.org/10.3390/ijerph20043470 |
work_keys_str_mv | AT chebetmartin highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT musabamiltonw highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT mukunyadavid highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT makokobrian highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT napyoagnes highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT nantaleritah highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT aumaproscovia highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT atimketty highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT nahuriradoreck highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT leeseungwon highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT okellodedan highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT ssegawalawrence highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT bromleykieran highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT burgoinekathy highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT ndeezigrace highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT tumwinejamesk highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT wandabwajulius highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy AT kigulisarah highburdenofneurodevelopmentaldelayamongchildrenborntowomenwithobstructedlabourineasternugandaacohortstudy |