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Pangenomic analysis reveals plant NAD(+) manipulation as an important virulence activity of bacterial pathogen effectors

Nicotinamide adenine dinucleotide (NAD(+)) has emerged as a key component in prokaryotic and eukaryotic immune systems. The recent discovery that Toll/interleukin-1 receptor (TIR) proteins function as NAD(+) hydrolases (NADase) links NAD(+)-derived small molecules with immune signaling. We investiga...

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Detalles Bibliográficos
Autores principales: Hulin, Michelle T., Hill, Lionel, Jones, Jonathan D. G., Ma, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963460/
https://www.ncbi.nlm.nih.gov/pubmed/36753463
http://dx.doi.org/10.1073/pnas.2217114120

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