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Influence of Age and Sex on the Pharmacokinetics of Midazolam and the Depth of Sedation in Pediatric Patients Undergoing Minor Surgeries

Whether age and sex influence the depth of sedation and the pharmacokinetics of midazolam is currently unknown. The influence of age and sex was investigated in 117 children (2 to 17 years) who required intravenous sedation for minor surgery (0.05 mg/kg). Plasma concentrations and sedation effects w...

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Detalles Bibliográficos
Autores principales: Flores-Pérez, Carmen, Flores-Pérez, Janett, Moreno-Rocha, Luis Alfonso, Chávez-Pacheco, Juan Luis, Noguez-Méndez, Norma Angélica, Ramírez-Mendiola, Blanca, Sánchez-Maza, Yolopsi, Sarmiento-Argüello, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963644/
https://www.ncbi.nlm.nih.gov/pubmed/36839762
http://dx.doi.org/10.3390/pharmaceutics15020440

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