Synthesis, Molecular Docking, and Bioactivity Study of Novel Hybrid Benzimidazole Urea Derivatives: A Promising α-Amylase and α-Glucosidase Inhibitor Candidate with Antioxidant Activity

A novel series of benzimidazole ureas 3a–h were elaborated using 2-(1H-benzoimidazol-2-yl) aniline 1 and the appropriate isocyanates 2a–h. The antioxidant and possible antidiabetic activities of the target benzimidazole-ureas 3a–h were evaluated. Almost all compounds 3a–h displayed strong to moderat...

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Detalles Bibliográficos
Autores principales: Aroua, Lotfi M., Alosaimi, Abdulelah H., Alminderej, Fahad M., Messaoudi, Sabri, Mohammed, Hamdoon A., Almahmoud, Suliman A., Chigurupati, Sridevi, Albadri, Abuzar E. A. E., Mekni, Nejib H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963656/
https://www.ncbi.nlm.nih.gov/pubmed/36839780
http://dx.doi.org/10.3390/pharmaceutics15020457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963656/
https://www.ncbi.nlm.nih.gov/pubmed/36839780
http://dx.doi.org/10.3390/pharmaceutics15020457

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