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Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems

Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids “Solutions for Your Success” have received a lot of interest from scientists due to a myriad of applications in the pharmac...

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Autores principales: Shukla, Monu Kumar, Tiwari, Harshita, Verma, Rachna, Dong, Wen-Liang, Azizov, Shavkatjon, Kumar, Brajesh, Pandey, Sadanand, Kumar, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963759/
https://www.ncbi.nlm.nih.gov/pubmed/36840024
http://dx.doi.org/10.3390/pharmaceutics15020702
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author Shukla, Monu Kumar
Tiwari, Harshita
Verma, Rachna
Dong, Wen-Liang
Azizov, Shavkatjon
Kumar, Brajesh
Pandey, Sadanand
Kumar, Deepak
author_facet Shukla, Monu Kumar
Tiwari, Harshita
Verma, Rachna
Dong, Wen-Liang
Azizov, Shavkatjon
Kumar, Brajesh
Pandey, Sadanand
Kumar, Deepak
author_sort Shukla, Monu Kumar
collection PubMed
description Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids “Solutions for Your Success” have received a lot of interest from scientists due to a myriad of applications in the pharmaceutical industry for drug delivery systems as well as targeting different diseases. Solubility is a critical physicochemical property that determines the drug’s fate at the target site. Many promising drug candidates fail in various phases of drug research due to poor solubility. In this context, ionic liquids are regarded as effective drug delivery systems for poorly soluble medicines. ILs are also able to combine different anions/cations with other cations/anions to produce salts that satisfy the concept behind the ILs. The important characteristics of ionic liquids are the modularity of their physicochemical properties depending on the application. The review highlights the recent advancement and further applications of ionic liquids to deliver drugs in the pharmaceutical and biomedical fields.
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spelling pubmed-99637592023-02-26 Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems Shukla, Monu Kumar Tiwari, Harshita Verma, Rachna Dong, Wen-Liang Azizov, Shavkatjon Kumar, Brajesh Pandey, Sadanand Kumar, Deepak Pharmaceutics Review Advancements in the fields of ionic liquids (ILs) broaden its applications not only in traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids “Solutions for Your Success” have received a lot of interest from scientists due to a myriad of applications in the pharmaceutical industry for drug delivery systems as well as targeting different diseases. Solubility is a critical physicochemical property that determines the drug’s fate at the target site. Many promising drug candidates fail in various phases of drug research due to poor solubility. In this context, ionic liquids are regarded as effective drug delivery systems for poorly soluble medicines. ILs are also able to combine different anions/cations with other cations/anions to produce salts that satisfy the concept behind the ILs. The important characteristics of ionic liquids are the modularity of their physicochemical properties depending on the application. The review highlights the recent advancement and further applications of ionic liquids to deliver drugs in the pharmaceutical and biomedical fields. MDPI 2023-02-20 /pmc/articles/PMC9963759/ /pubmed/36840024 http://dx.doi.org/10.3390/pharmaceutics15020702 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Shukla, Monu Kumar
Tiwari, Harshita
Verma, Rachna
Dong, Wen-Liang
Azizov, Shavkatjon
Kumar, Brajesh
Pandey, Sadanand
Kumar, Deepak
Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems
title Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems
title_full Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems
title_fullStr Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems
title_full_unstemmed Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems
title_short Role and Recent Advancements of Ionic Liquids in Drug Delivery Systems
title_sort role and recent advancements of ionic liquids in drug delivery systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963759/
https://www.ncbi.nlm.nih.gov/pubmed/36840024
http://dx.doi.org/10.3390/pharmaceutics15020702
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