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“Self-inactivating” rabies viruses are susceptible to loss of their intended attenuating modification

Monosynaptic tracing using rabies virus is an important technique in neuroscience, allowing brain-wide labeling of neurons directly presynaptic to a targeted neuronal population. A 2017 article reported the development of a noncytotoxic version—a major advance—based on attenuating the rabies virus b...

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Detalles Bibliográficos
Autores principales: Jin, Lei, Matsuyama, Makoto, Sullivan, Heather A., Zhu, Mulangma, Lavin, Thomas K., Hou, YuanYuan, Lea, Nicholas E., Pruner, Maxwell T., Dam Ferdínez, María Lucía, Wickersham, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963760/
https://www.ncbi.nlm.nih.gov/pubmed/37053554
http://dx.doi.org/10.1073/pnas.2023481120