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“Self-inactivating” rabies viruses are susceptible to loss of their intended attenuating modification
Monosynaptic tracing using rabies virus is an important technique in neuroscience, allowing brain-wide labeling of neurons directly presynaptic to a targeted neuronal population. A 2017 article reported the development of a noncytotoxic version—a major advance—based on attenuating the rabies virus b...
Autores principales: | Jin, Lei, Matsuyama, Makoto, Sullivan, Heather A., Zhu, Mulangma, Lavin, Thomas K., Hou, YuanYuan, Lea, Nicholas E., Pruner, Maxwell T., Dam Ferdínez, María Lucía, Wickersham, Ian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963760/ https://www.ncbi.nlm.nih.gov/pubmed/37053554 http://dx.doi.org/10.1073/pnas.2023481120 |
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