A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB

Autophagy supports the fast growth of established tumors and promotes tumor resistance to multiple treatments. Inhibition of autophagy is a promising strategy for tumor therapy. However, effective autophagy inhibitors suitable for clinical use are currently lacking. There is a high demand for identi...

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Detalles Bibliográficos
Autores principales: Lin, Yuqi, Shi, Qiqi, Yang, Guang, Shi, Fuchun, Zhou, Yang, Wang, Tongtong, Xu, Peng, Li, Peifeng, Liu, Zaizhou, Sun, Hanyin, Zhao, Zhixin, Ding, Ke, Wang, Zhen, Feng, Haizhong, Yu, Biao, Fang, Pengfei, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963785/
https://www.ncbi.nlm.nih.gov/pubmed/36749723
http://dx.doi.org/10.1073/pnas.2213670120

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