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Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study

Technological progress, such as the launching of a new generation of drug-coated stents as well as new antiplatelet drugs, has resulted in the treatment of myocardial infarction (MI) becoming much more effective. The aim of this study was to assess in-hospital mortality and to conduct an assessment...

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Autores principales: Gawinski, Lukasz, Burzynska, Monika, Marczak, Michal, Kozlowski, Remigiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963836/
https://www.ncbi.nlm.nih.gov/pubmed/36834296
http://dx.doi.org/10.3390/ijerph20043603
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author Gawinski, Lukasz
Burzynska, Monika
Marczak, Michal
Kozlowski, Remigiusz
author_facet Gawinski, Lukasz
Burzynska, Monika
Marczak, Michal
Kozlowski, Remigiusz
author_sort Gawinski, Lukasz
collection PubMed
description Technological progress, such as the launching of a new generation of drug-coated stents as well as new antiplatelet drugs, has resulted in the treatment of myocardial infarction (MI) becoming much more effective. The aim of this study was to assess in-hospital mortality and to conduct an assessment of risk factors relevant to the in-hospital death of patients with MI. This study was based on an observational hospital registry of patients with MI (ACS GRU registry). For the purpose of the statistical analysis of the risk factors of death, a univariate logistic regression model was applied. In-hospital general mortality amounted to 7.27%. A higher death risk was confirmed in the following cases: (1) serious adverse events (SAEs) that occurred during the procedure; (2) patients transferred from another department of a hospital (OR = 2.647, p = 0.0056); (3) primary percutaneous coronary angioplasty performed on weekdays between 10 p.m. and 8 a.m. (OR = 2.540, p = 0.0146). The influence of workload and operator experience on the risk of death in a patient with MI has not been confirmed. The results of this study indicate the increasing importance of new risk factors for in-hospital death in patients with MI, such as selected logistical aspects of the MI treatment process and individual SAEs.
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spelling pubmed-99638362023-02-26 Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study Gawinski, Lukasz Burzynska, Monika Marczak, Michal Kozlowski, Remigiusz Int J Environ Res Public Health Article Technological progress, such as the launching of a new generation of drug-coated stents as well as new antiplatelet drugs, has resulted in the treatment of myocardial infarction (MI) becoming much more effective. The aim of this study was to assess in-hospital mortality and to conduct an assessment of risk factors relevant to the in-hospital death of patients with MI. This study was based on an observational hospital registry of patients with MI (ACS GRU registry). For the purpose of the statistical analysis of the risk factors of death, a univariate logistic regression model was applied. In-hospital general mortality amounted to 7.27%. A higher death risk was confirmed in the following cases: (1) serious adverse events (SAEs) that occurred during the procedure; (2) patients transferred from another department of a hospital (OR = 2.647, p = 0.0056); (3) primary percutaneous coronary angioplasty performed on weekdays between 10 p.m. and 8 a.m. (OR = 2.540, p = 0.0146). The influence of workload and operator experience on the risk of death in a patient with MI has not been confirmed. The results of this study indicate the increasing importance of new risk factors for in-hospital death in patients with MI, such as selected logistical aspects of the MI treatment process and individual SAEs. MDPI 2023-02-17 /pmc/articles/PMC9963836/ /pubmed/36834296 http://dx.doi.org/10.3390/ijerph20043603 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gawinski, Lukasz
Burzynska, Monika
Marczak, Michal
Kozlowski, Remigiusz
Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study
title Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study
title_full Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study
title_fullStr Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study
title_full_unstemmed Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study
title_short Assessment of In-Hospital Mortality and Its Risk Factors in Patients with Myocardial Infarction Considering the Logistical Aspects of the Treatment Process—A Single-Center, Retrospective, Observational Study
title_sort assessment of in-hospital mortality and its risk factors in patients with myocardial infarction considering the logistical aspects of the treatment process—a single-center, retrospective, observational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963836/
https://www.ncbi.nlm.nih.gov/pubmed/36834296
http://dx.doi.org/10.3390/ijerph20043603
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