In Vitro and In Vivo Characterisation of a Mucoadhesive Buccal Film Loaded with Doxycycline Hyclate for Topical Application in Periodontitis

Mucoadhesive films loaded with doxycycline hyclate (Doxy Hyc), consisting of mixtures of hydroxypropylmethyl cellulose (HPMC) E3, K4 and polyacrylic acid (Carbopol 940), were prepared by casting method, aiming to design a formulation intended for application in the oral cavity. The obtained film for...

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Detalles Bibliográficos
Autores principales: Dinte, Elena, Muntean, Dana Maria, Andrei, Vlad, Boșca, Bianca Adina, Dudescu, Cristian Mircea, Barbu-Tudoran, Lucian, Borodi, Gheorghe, Andrei, Sanda, Gal, Adrian Florin, Rus, Vasile, Gherman, Luciana-Mădălina, Cadar, Oana, Barabas, Reka, Niculae, Mihaela, Ilea, Aranka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963859/
https://www.ncbi.nlm.nih.gov/pubmed/36839899
http://dx.doi.org/10.3390/pharmaceutics15020580

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