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Self-regulation of the nuclear pore complex enables clogging-free crowded transport
Nuclear pore complexes (NPCs) are the main conduits for macromolecular transport into and out of the nucleus of eukaryotic cells. The central component of the NPC transport mechanism is an assembly of intrinsically disordered proteins (IDPs) that fills the NPC channel. The channel interior is furthe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963888/ https://www.ncbi.nlm.nih.gov/pubmed/36757893 http://dx.doi.org/10.1073/pnas.2212874120 |