Cargando…

The Dynamic Linkage between Provirus Integration Sites and the Host Functional Genome Property Alongside HIV-1 Infections Associated with Antiretroviral Therapy

(1) Background: The HIV-1 latent reservoir harboring replication-competent proviruses is the major barrier in the quest for an HIV-1 infection cure. HIV-1 infection at all stages of disease progression is associated with immune activation and dysfunctional production of proinflammatory soluble facto...

Descripción completa

Detalles Bibliográficos
Autor principal:	Chen, Heng-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963931/ https://www.ncbi.nlm.nih.gov/pubmed/36851277 http://dx.doi.org/10.3390/vaccines11020402

Ejemplares similares

Droplet microfluidic sequencing of HIV proviruses with their integration sites in patients receiving antiretroviral therapy
por: Sun, Chen, et al.
Publicado: (2022)

Antiretroviral APOBEC3 cytidine deaminases alter HIV-1 provirus integration site profiles
por: Ajoge, Hannah O., et al.
Publicado: (2023)

The chromatin landscape at the HIV-1 provirus integration site determines viral expression
por: Vansant, Gerlinde, et al.
Publicado: (2020)

Integration sites of the HTLV-1 provirus in host human genome in the IDH patients with monoclonal integration
por: Argolo, Juliana M, et al.
Publicado: (2011)

Persistence of intact HIV-1 proviruses in the brain during antiretroviral therapy
por: Sun, Weiwei, et al.
Publicado: (2023)

Persistence of intact HIV-1 proviruses in the brain during antiretroviral therapy
por: Sun, Weiwei, et al.
Publicado: (2023)

Transcriptional provirus silencing in the context of the integration site environment
por: Šenigl, Filip, et al.
Publicado: (2013)

Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy
por: White, Jennifer A., et al.
Publicado: (2022)

Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection
por: Rainwater-Lovett, Kaitlin, et al.
Publicado: (2017)

HIV Provirus Stably Reproduces Parental Latent and Induced Transcription Phenotypes Regardless of the Chromosomal Integration Site
por: Hashemi, Farhad B., et al.
Publicado: (2016)

Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses
por: Einkauf, Kevin B., et al.
Publicado: (2022)

Intact provirus and integration sites analysis in acute HIV-1 infection and changes after one year of early antiviral therapy
por: Rozera, Gabriella, et al.
Publicado: (2022)

Challenges in Quantifying Cytosine Methylation in the HIV Provirus
por: LaMere, Sarah A., et al.
Publicado: (2019)

HIV-1 gene expression: lessons from provirus and non-integrated DNA
por: Wu, Yuntao
Publicado: (2004)

Single-Cell Imaging Shows That the Transcriptional State of the HIV-1 Provirus and Its Reactivation Potential Depend on the Integration Site
por: Janssens, Julie, et al.
Publicado: (2022)

Intranuclear Positions of HIV-1 Proviruses Are Dynamic and Do Not Correlate with Transcriptional Activity
por: Burdick, Ryan C., et al.
Publicado: (2022)

Long-term persistence of transcriptionally active ‘defective’ HIV-1 proviruses: implications for persistent immune activation during antiretroviral therapy
por: Singh, Kanal, et al.
Publicado: (2023)

The host genomic environment of the provirus determines the abundance of HTLV-1–infected T-cell clones
por: Gillet, Nicolas A., et al.
Publicado: (2011)

CRISPR/Cas9 Genome Editing to Disable the Latent HIV-1 Provirus
por: Panfil, Amanda R., et al.
Publicado: (2018)

HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus
por: Musick, Andrew, et al.
Publicado: (2019)

On the generation of the MSD-Ѱ class of defective HIV proviruses
por: Das, Atze T., et al.
Publicado: (2019)

Defective HIV-1 proviruses produce viral proteins
por: Imamichi, Hiromi, et al.
Publicado: (2020)

Impact of misclassified defective proviruses on HIV reservoir measurements
por: Reeves, Daniel B., et al.
Publicado: (2023)

The structure and genomic integration site of the HTLV-1 provirus determine selective clonal expansion and transformation to adult T cell leukaemia/lymphoma
por: Cook, Lucy B, et al.
Publicado: (2014)

The Integrated HIV-1 Provirus in Patient Sperm Chromosome and Its Transfer into the Early Embryo by Fertilization
por: Wang, Dian, et al.
Publicado: (2011)

Transcriptional provirus silencing as a crosstalk of de novo DNA methylation and epigenomic features at the integration site
por: Šenigl, Filip, et al.
Publicado: (2012)

Assessing the effects of antiretroviral therapy-latency-reversing agent combination therapy on eradicating replication-competent HIV provirus in a Jurkat cell culture model
por: Matsuda, Kouki, et al.
Publicado: (2023)

Digital detection of endonuclease mediated gene disruption in the HIV provirus
por: Sedlak, Ruth Hall, et al.
Publicado: (2016)

Targeting and Understanding HIV Latency: The CRISPR System against the Provirus
por: Magro, Gloria, et al.
Publicado: (2021)

Activation of HIV-1 proviruses increases downstream chromatin accessibility
por: Shah, Raven, et al.
Publicado: (2022)

HIV reservoirs are dominated by genetically younger and clonally enriched proviruses
por: Kinloch, Natalie N., et al.
Publicado: (2023)

Chromatin control of Tat-mediated reactivation of latent HIV-1 provirus
por: Masse, Guillemette X, et al.
Publicado: (2009)

Defective proviruses rapidly accumulate during acute HIV-1 infection
por: Bruner, Katherine M., et al.
Publicado: (2016)

Intragenic proviral elements support transcription of defective HIV-1 proviruses
por: Kuniholm, Jeffrey, et al.
Publicado: (2021)

Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART
por: Cochrane, Catherine R., et al.
Publicado: (2022)

Linkage to HIV Care and Antiretroviral Therapy in Cape Town, South Africa
por: Kranzer, Katharina, et al.
Publicado: (2010)

Insertion of sequences at the original provirus integration site of mouse ROSA26 locus using the CRISPR/Cas9 system
por: Quadros, Rolen M., et al.
Publicado: (2015)

Growth rate determines prokaryote-provirus network modulated by temperature and host genetic traits
por: Liu, Zhenghua, et al.
Publicado: (2022)

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
por: Ebina, Hirotaka, et al.
Publicado: (2013)

Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1
por: Tyagi, Mudit, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_11tq1pmiocpobbasuvkuq03h9d