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Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis

Genetic studies have identified ≥240 loci associated with the risk of type 2 diabetes (T2D), yet most of these loci lie in non-coding regions, masking the underlying molecular mechanisms. Recent studies investigating mRNA expression in human pancreatic islets have yielded important insights into the...

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Detalles Bibliográficos
Autores principales: Taylor, Henry J., Hung, Yu-Han, Narisu, Narisu, Erdos, Michael R., Kanke, Matthew, Yan, Tingfen, Grenko, Caleb M., Swift, Amy J., Bonnycastle, Lori L., Sethupathy, Praveen, Collins, Francis S., Taylor, D. Leland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963967/
https://www.ncbi.nlm.nih.gov/pubmed/36757889
http://dx.doi.org/10.1073/pnas.2206797120