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Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned?
Lung cancer screening (LCS) programs through low-dose Computed Tomography (LDCT) are being implemented in several countries worldwide. Radiation exposure of healthy individuals due to prolonged CT screening rounds and, eventually, the additional examinations required in case of suspicious findings m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964027/ https://www.ncbi.nlm.nih.gov/pubmed/36828367 http://dx.doi.org/10.3390/tomography9010015 |
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author | Pozzessere, Chiara von Garnier, Christophe Beigelman-Aubry, Catherine |
author_facet | Pozzessere, Chiara von Garnier, Christophe Beigelman-Aubry, Catherine |
author_sort | Pozzessere, Chiara |
collection | PubMed |
description | Lung cancer screening (LCS) programs through low-dose Computed Tomography (LDCT) are being implemented in several countries worldwide. Radiation exposure of healthy individuals due to prolonged CT screening rounds and, eventually, the additional examinations required in case of suspicious findings may represent a concern, thus eventually reducing the participation in an LCS program. Therefore, the present review aims to assess the potential radiation risk from LDCT in this setting, providing estimates of cumulative dose and radiation-related risk in LCS in order to improve awareness for an informed and complete attendance to the program. After summarizing the results of the international trials on LCS to introduce the benefits coming from the implementation of a dedicated program, the screening-related and participant-related factors determining the radiation risk will be introduced and their burden assessed. Finally, future directions for a personalized screening program as well as technical improvements to reduce the delivered dose will be presented. |
format | Online Article Text |
id | pubmed-9964027 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99640272023-02-26 Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? Pozzessere, Chiara von Garnier, Christophe Beigelman-Aubry, Catherine Tomography Review Lung cancer screening (LCS) programs through low-dose Computed Tomography (LDCT) are being implemented in several countries worldwide. Radiation exposure of healthy individuals due to prolonged CT screening rounds and, eventually, the additional examinations required in case of suspicious findings may represent a concern, thus eventually reducing the participation in an LCS program. Therefore, the present review aims to assess the potential radiation risk from LDCT in this setting, providing estimates of cumulative dose and radiation-related risk in LCS in order to improve awareness for an informed and complete attendance to the program. After summarizing the results of the international trials on LCS to introduce the benefits coming from the implementation of a dedicated program, the screening-related and participant-related factors determining the radiation risk will be introduced and their burden assessed. Finally, future directions for a personalized screening program as well as technical improvements to reduce the delivered dose will be presented. MDPI 2023-01-24 /pmc/articles/PMC9964027/ /pubmed/36828367 http://dx.doi.org/10.3390/tomography9010015 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pozzessere, Chiara von Garnier, Christophe Beigelman-Aubry, Catherine Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
title | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
title_full | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
title_fullStr | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
title_full_unstemmed | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
title_short | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
title_sort | radiation exposure to low-dose computed tomography for lung cancer screening: should we be concerned? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964027/ https://www.ncbi.nlm.nih.gov/pubmed/36828367 http://dx.doi.org/10.3390/tomography9010015 |
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