Tin(II) and Tin(IV) Complexes Incorporating the Oxygen Tripodal Ligands [(η(5)-C(5)R(5))Co{P(OEt)(2)O}(3)](−), (R = H, Me; Et = -C(2)H(5)) as Potent Inflammatory Mediator Inhibitors: Cytotoxic Properties and Biological Activities against the Platelet-Activating Factor (PAF) and Thrombin

Metal complexes displaying antiplatelet properties is a promising research area. In our methodology, Platelet-Activating Factor (PAF), the most potent lipid pro-inflammatory mediator, serves as a biological probe. The antiplatelet activity is exerted by the inhibition of the PAF-induced aggregation...

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Detalles Bibliográficos
Autores principales: Kalampalidis, Alexandros, Damati, Artemis, Matthopoulos, Demetrios, Tsoupras, Alexandros B., Demopoulos, Constantinos A., Schnakenburg, Gregor, Philippopoulos, Athanassios I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964123/
https://www.ncbi.nlm.nih.gov/pubmed/36838847
http://dx.doi.org/10.3390/molecules28041859

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