Cargando…

Advances in Self-Assembled Peptides as Drug Carriers

In recent years, self-assembled peptide nanotechnology has attracted a great deal of attention for its ability to form various regular and ordered structures with diverse and practical functions. Self-assembled peptides can exist in different environments and are a kind of medical bio-regenerative m...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Yawen, Wang, Lele, Zhang, Xue, Zhou, Ziling, Shen, Xinzhu, Hu, Haodong, Sun, Rui, Tang, Jihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964150/
https://www.ncbi.nlm.nih.gov/pubmed/36839803
http://dx.doi.org/10.3390/pharmaceutics15020482
_version_ 1784896431405924352
author Gao, Yawen
Wang, Lele
Zhang, Xue
Zhou, Ziling
Shen, Xinzhu
Hu, Haodong
Sun, Rui
Tang, Jihui
author_facet Gao, Yawen
Wang, Lele
Zhang, Xue
Zhou, Ziling
Shen, Xinzhu
Hu, Haodong
Sun, Rui
Tang, Jihui
author_sort Gao, Yawen
collection PubMed
description In recent years, self-assembled peptide nanotechnology has attracted a great deal of attention for its ability to form various regular and ordered structures with diverse and practical functions. Self-assembled peptides can exist in different environments and are a kind of medical bio-regenerative material with unique structures. These materials have good biocompatibility and controllability and can form nanoparticles, nanofibers and hydrogels to perform specific morphological functions, which are widely used in biomedical and material science fields. In this paper, the properties of self-assembled peptides, their influencing factors and the nanostructures that they form are reviewed, and the applications of self-assembled peptides as drug carriers are highlighted. Finally, the prospects and challenges for developing self-assembled peptide nanomaterials are briefly discussed.
format Online
Article
Text
id pubmed-9964150
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99641502023-02-26 Advances in Self-Assembled Peptides as Drug Carriers Gao, Yawen Wang, Lele Zhang, Xue Zhou, Ziling Shen, Xinzhu Hu, Haodong Sun, Rui Tang, Jihui Pharmaceutics Review In recent years, self-assembled peptide nanotechnology has attracted a great deal of attention for its ability to form various regular and ordered structures with diverse and practical functions. Self-assembled peptides can exist in different environments and are a kind of medical bio-regenerative material with unique structures. These materials have good biocompatibility and controllability and can form nanoparticles, nanofibers and hydrogels to perform specific morphological functions, which are widely used in biomedical and material science fields. In this paper, the properties of self-assembled peptides, their influencing factors and the nanostructures that they form are reviewed, and the applications of self-assembled peptides as drug carriers are highlighted. Finally, the prospects and challenges for developing self-assembled peptide nanomaterials are briefly discussed. MDPI 2023-02-01 /pmc/articles/PMC9964150/ /pubmed/36839803 http://dx.doi.org/10.3390/pharmaceutics15020482 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gao, Yawen
Wang, Lele
Zhang, Xue
Zhou, Ziling
Shen, Xinzhu
Hu, Haodong
Sun, Rui
Tang, Jihui
Advances in Self-Assembled Peptides as Drug Carriers
title Advances in Self-Assembled Peptides as Drug Carriers
title_full Advances in Self-Assembled Peptides as Drug Carriers
title_fullStr Advances in Self-Assembled Peptides as Drug Carriers
title_full_unstemmed Advances in Self-Assembled Peptides as Drug Carriers
title_short Advances in Self-Assembled Peptides as Drug Carriers
title_sort advances in self-assembled peptides as drug carriers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964150/
https://www.ncbi.nlm.nih.gov/pubmed/36839803
http://dx.doi.org/10.3390/pharmaceutics15020482
work_keys_str_mv AT gaoyawen advancesinselfassembledpeptidesasdrugcarriers
AT wanglele advancesinselfassembledpeptidesasdrugcarriers
AT zhangxue advancesinselfassembledpeptidesasdrugcarriers
AT zhouziling advancesinselfassembledpeptidesasdrugcarriers
AT shenxinzhu advancesinselfassembledpeptidesasdrugcarriers
AT huhaodong advancesinselfassembledpeptidesasdrugcarriers
AT sunrui advancesinselfassembledpeptidesasdrugcarriers
AT tangjihui advancesinselfassembledpeptidesasdrugcarriers