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Vulvar Lichen Planus Presenting as Chronic Vulvar Purpura
Background: There is a broad spectrum of vulvar pigmented lesions that differ based on their histopathological and clinical features. Chronic vulvar purpura is a rare entity, associated with a broad morphological spectrum, from lichen aureus, Zoon’s vulvitis, pigmented purpuric dermatosis and with l...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964276/ https://www.ncbi.nlm.nih.gov/pubmed/36837408 http://dx.doi.org/10.3390/medicina59020206 |
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author | Luzar, Boštjan Truden, Anamarija Turk, Lara Janša, Vid Lewis, Fiona Calonje, Eduardo Smrkolj, Špela |
author_facet | Luzar, Boštjan Truden, Anamarija Turk, Lara Janša, Vid Lewis, Fiona Calonje, Eduardo Smrkolj, Špela |
author_sort | Luzar, Boštjan |
collection | PubMed |
description | Background: There is a broad spectrum of vulvar pigmented lesions that differ based on their histopathological and clinical features. Chronic vulvar purpura is a rare entity, associated with a broad morphological spectrum, from lichen aureus, Zoon’s vulvitis, pigmented purpuric dermatosis and with lichen planus as in our case. Case presentation: In this article we discuss a case of an 86-year-old white woman with hyperpigmentation on her upper vulva, next to the introitus, with complaints of urine incontinence. Biopsy revealed subepithelial stromal lichenoid inflammatory infiltrate containing plasma cells, lymphocytes and some neutrophilic granulocytes as well as dilated and congested vessels. Hemosiderin deposits and erythrocyte extravasation were found. There was evidence of hyperkeratosis with hyper granulosis and erosions. Spongiosis was also noted. Few melanocytes were identified with no sign of malignancy. These findings correlate with the diagnosis of vulvar lichen planus. Conclusions: Chronic vulvar purpura is a clinical term used for different chronic inflammatory dermatoses presenting as red bluish or violaceous discolorations on the vulva, often associated with cayenne-pepper-like speckling. Considering a great overlap of possible diseases, the final diagnosis could be challenging. It is important to exclude a melanocytic tumour in these cases. |
format | Online Article Text |
id | pubmed-9964276 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99642762023-02-26 Vulvar Lichen Planus Presenting as Chronic Vulvar Purpura Luzar, Boštjan Truden, Anamarija Turk, Lara Janša, Vid Lewis, Fiona Calonje, Eduardo Smrkolj, Špela Medicina (Kaunas) Case Report Background: There is a broad spectrum of vulvar pigmented lesions that differ based on their histopathological and clinical features. Chronic vulvar purpura is a rare entity, associated with a broad morphological spectrum, from lichen aureus, Zoon’s vulvitis, pigmented purpuric dermatosis and with lichen planus as in our case. Case presentation: In this article we discuss a case of an 86-year-old white woman with hyperpigmentation on her upper vulva, next to the introitus, with complaints of urine incontinence. Biopsy revealed subepithelial stromal lichenoid inflammatory infiltrate containing plasma cells, lymphocytes and some neutrophilic granulocytes as well as dilated and congested vessels. Hemosiderin deposits and erythrocyte extravasation were found. There was evidence of hyperkeratosis with hyper granulosis and erosions. Spongiosis was also noted. Few melanocytes were identified with no sign of malignancy. These findings correlate with the diagnosis of vulvar lichen planus. Conclusions: Chronic vulvar purpura is a clinical term used for different chronic inflammatory dermatoses presenting as red bluish or violaceous discolorations on the vulva, often associated with cayenne-pepper-like speckling. Considering a great overlap of possible diseases, the final diagnosis could be challenging. It is important to exclude a melanocytic tumour in these cases. MDPI 2023-01-20 /pmc/articles/PMC9964276/ /pubmed/36837408 http://dx.doi.org/10.3390/medicina59020206 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Luzar, Boštjan Truden, Anamarija Turk, Lara Janša, Vid Lewis, Fiona Calonje, Eduardo Smrkolj, Špela Vulvar Lichen Planus Presenting as Chronic Vulvar Purpura |
title | Vulvar Lichen Planus Presenting as Chronic Vulvar Purpura |
title_full | Vulvar Lichen Planus Presenting as Chronic Vulvar Purpura |
title_fullStr | Vulvar Lichen Planus Presenting as Chronic Vulvar Purpura |
title_full_unstemmed | Vulvar Lichen Planus Presenting as Chronic Vulvar Purpura |
title_short | Vulvar Lichen Planus Presenting as Chronic Vulvar Purpura |
title_sort | vulvar lichen planus presenting as chronic vulvar purpura |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964276/ https://www.ncbi.nlm.nih.gov/pubmed/36837408 http://dx.doi.org/10.3390/medicina59020206 |
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