Biodistribution of Intratracheal, Intranasal, and Intravenous Injections of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles in a Mouse Model for Drug Delivery Studies

Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are extensively studied as therapeutic tools. Evaluation of their biodistribution is fundamental to understanding MSC-EVs’ impact on target organs. In our work, MSC-EVs were initially labeled with DiR, a fluorescent lipophilic dye, an...

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Detalles Bibliográficos
Autores principales: Tolomeo, Anna Maria, Zuccolotto, Gaia, Malvicini, Ricardo, De Lazzari, Giada, Penna, Alessandro, Franco, Chiara, Caicci, Federico, Magarotto, Fabio, Quarta, Santina, Pozzobon, Michela, Rosato, Antonio, Muraca, Maurizio, Collino, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964290/
https://www.ncbi.nlm.nih.gov/pubmed/36839873
http://dx.doi.org/10.3390/pharmaceutics15020548

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