Olea europaea Leaf Phenolics Oleuropein, Hydroxytyrosol, Tyrosol, and Rutin Induce Apoptosis and Additionally Affect Temozolomide against Glioblastoma: In Particular, Oleuropein Inhibits Spheroid Growth by Attenuating Stem-like Cell Phenotype

The effects of Olea europaea leaf extract (OLE) phenolics, including oleuropein (OL), hydroxytyrosol (HT), tyrosol (TYR), and rutin against glioblastoma (GB), independently and in combination with temozolomide (TMZ), were investigated in T98G and A172 cells. Cell growth was assessed by WST-1, real-t...

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Detalles Bibliográficos
Autores principales: Ercelik, Melis, Tekin, Cagla, Tezcan, Gulcin, Ak Aksoy, Secil, Bekar, Ahmet, Kocaeli, Hasan, Taskapilioglu, Mevlut Ozgur, Eser, Pınar, Tunca, Berrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964321/
https://www.ncbi.nlm.nih.gov/pubmed/36836827
http://dx.doi.org/10.3390/life13020470

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