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Antioxidant and Antidiabetic Activity of Algae

Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes...

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Detalles Bibliográficos
Autores principales: Abo-Shady, Atef Mohamed, Gheda, Saly Farouk, Ismail, Gehan Ahmed, Cotas, João, Pereira, Leonel, Abdel-Karim, Omnia Hamdy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964347/
https://www.ncbi.nlm.nih.gov/pubmed/36836817
http://dx.doi.org/10.3390/life13020460
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author Abo-Shady, Atef Mohamed
Gheda, Saly Farouk
Ismail, Gehan Ahmed
Cotas, João
Pereira, Leonel
Abdel-Karim, Omnia Hamdy
author_facet Abo-Shady, Atef Mohamed
Gheda, Saly Farouk
Ismail, Gehan Ahmed
Cotas, João
Pereira, Leonel
Abdel-Karim, Omnia Hamdy
author_sort Abo-Shady, Atef Mohamed
collection PubMed
description Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes mellitus, a metabolic illness, is the third largest cause of death globally. The hunt for an efficient natural-based antidiabetic therapy is crucial to battling diabetes and the associated consequences due to the unfavorable side effects of currently available antidiabetic medications. Finding the possible advantages of algae for the control of diabetes is crucial for the creation of natural drugs. Many of algae’s metabolic processes produce bioactive secondary metabolites, which give algae their diverse chemical and biological features. Numerous studies have demonstrated the antioxidant and antidiabetic benefits of algae, mostly by blocking carbohydrate hydrolyzing enzyme activity, such as α-amylase and α-glucosidase. Additionally, bioactive components from algae can lessen diabetic symptoms in vivo. Therefore, the current review concentrates on the role of various secondary bioactive substances found naturally in algae and their potential as antioxidants and antidiabetic materials, as well as the urgent need to apply these substances in the pharmaceutical industry.
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spelling pubmed-99643472023-02-26 Antioxidant and Antidiabetic Activity of Algae Abo-Shady, Atef Mohamed Gheda, Saly Farouk Ismail, Gehan Ahmed Cotas, João Pereira, Leonel Abdel-Karim, Omnia Hamdy Life (Basel) Review Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes mellitus, a metabolic illness, is the third largest cause of death globally. The hunt for an efficient natural-based antidiabetic therapy is crucial to battling diabetes and the associated consequences due to the unfavorable side effects of currently available antidiabetic medications. Finding the possible advantages of algae for the control of diabetes is crucial for the creation of natural drugs. Many of algae’s metabolic processes produce bioactive secondary metabolites, which give algae their diverse chemical and biological features. Numerous studies have demonstrated the antioxidant and antidiabetic benefits of algae, mostly by blocking carbohydrate hydrolyzing enzyme activity, such as α-amylase and α-glucosidase. Additionally, bioactive components from algae can lessen diabetic symptoms in vivo. Therefore, the current review concentrates on the role of various secondary bioactive substances found naturally in algae and their potential as antioxidants and antidiabetic materials, as well as the urgent need to apply these substances in the pharmaceutical industry. MDPI 2023-02-07 /pmc/articles/PMC9964347/ /pubmed/36836817 http://dx.doi.org/10.3390/life13020460 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Abo-Shady, Atef Mohamed
Gheda, Saly Farouk
Ismail, Gehan Ahmed
Cotas, João
Pereira, Leonel
Abdel-Karim, Omnia Hamdy
Antioxidant and Antidiabetic Activity of Algae
title Antioxidant and Antidiabetic Activity of Algae
title_full Antioxidant and Antidiabetic Activity of Algae
title_fullStr Antioxidant and Antidiabetic Activity of Algae
title_full_unstemmed Antioxidant and Antidiabetic Activity of Algae
title_short Antioxidant and Antidiabetic Activity of Algae
title_sort antioxidant and antidiabetic activity of algae
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964347/
https://www.ncbi.nlm.nih.gov/pubmed/36836817
http://dx.doi.org/10.3390/life13020460
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