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Development, Validation and Application of a Bridging ELISA for Detection of Antibodies against GQ1001 in Cynomolgus Monkey Serum

Immunogenicity is a major issue associated with the PK, efficacy, and safety evaluation of therapeutic protein products during pre-clinical and clinical studies. A multi-tiered approach consisting of screening, confirmatory, and titration assays has been widely adopted for anti-drug antibody testing...

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Detalles Bibliográficos
Autores principales:	Liu, Tingting, Sun, Yajun, Deng, Xiaojie, Shi, Lili, Chen, Wenyi, Fang, Wenjing, Wu, Junliang, Fan, Xiaotian, Chen, Xiaoqiang, Sun, Jianhua, Qin, Gang, Gong, Likun, Qin, Qiuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964351/ https://www.ncbi.nlm.nih.gov/pubmed/36838672 http://dx.doi.org/10.3390/molecules28041684

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