Design, Synthesis and Phenotypic Profiling of Simplified Gedatolisib Analogues

Targeted antitumour therapy has revolutionized the treatment of several types of tumours. Among the validated targets, phosphatidylinositol-3 kinase (PI3K) deserves to be highlighted. Several PI3K inhibitors have been developed for the treatment of cancer, including gedatolisib (4). This inhibitor w...

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Detalles Bibliográficos
Autores principales: Costa, Caroline Marques Xavier, Aparecida-Silva, Cristiane, Gamba, Luis Eduardo Reina, de Melo, Thalita Neves, Barbosa, Gisele, de Moraes Junior, Manoel Oliveira, de Oliveira, Victoria Regina Thomaz, de Amorim, Carolinne Souza, Moraes, João A., Barreiro, Eliezer Jesus, Lima, Lídia Moreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964390/
https://www.ncbi.nlm.nih.gov/pubmed/37259357
http://dx.doi.org/10.3390/ph16020209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964390/
https://www.ncbi.nlm.nih.gov/pubmed/37259357
http://dx.doi.org/10.3390/ph16020209

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