Targeting the IGF-Axis in Cultured Pediatric High-Grade Glioma Cells Inhibits Cell Cycle Progression and Survival

Pediatric high-grade gliomas (pHGG) accounts for approximately 8–12% of primary brain tumors in children. Prognosis is poor, with a median survival of 9–15 months. Insulin-like growth factor 1-receptor (IGF-1R) gene amplifications have been identified in high-grade gliomas and may contribute to its...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yinhsuan Michely, Leibovitch, Matthew, Zeinieh, Michele, Jabado, Nada, Brodt, Pnina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964639/
https://www.ncbi.nlm.nih.gov/pubmed/37259440
http://dx.doi.org/10.3390/ph16020297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964639/
https://www.ncbi.nlm.nih.gov/pubmed/37259440
http://dx.doi.org/10.3390/ph16020297

Ejemplares similares