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Targeting the IGF-Axis in Cultured Pediatric High-Grade Glioma Cells Inhibits Cell Cycle Progression and Survival

Pediatric high-grade gliomas (pHGG) accounts for approximately 8–12% of primary brain tumors in children. Prognosis is poor, with a median survival of 9–15 months. Insulin-like growth factor 1-receptor (IGF-1R) gene amplifications have been identified in high-grade gliomas and may contribute to its...

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Detalles Bibliográficos
Autores principales:	Chen, Yinhsuan Michely, Leibovitch, Matthew, Zeinieh, Michele, Jabado, Nada, Brodt, Pnina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964639/ https://www.ncbi.nlm.nih.gov/pubmed/37259440 http://dx.doi.org/10.3390/ph16020297

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