Cargando…

An Overview of Physiologically-Based Pharmacokinetic Models for Forensic Science

A physiologically-based pharmacokinetic (PBPK) model represents the structural components of the body with physiologically relevant compartments connected via blood flow rates described by mathematical equations to determine drug disposition. PBPK models are used in the pharmaceutical sector for dru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fairman, Kiara, Choi, Me-Kyoung, Gonnabathula, Pavani, Lumen, Annie, Worth, Andrew, Paini, Alicia, Li, Miao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964742/ https://www.ncbi.nlm.nih.gov/pubmed/36851001 http://dx.doi.org/10.3390/toxics11020126

Ejemplares similares

Capturing the applicability of in vitro-in silico membrane transporter data in chemical risk assessment and biomedical research
por: Clerbaux, Laure-Alix, et al.
Publicado: (2018)

Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives
por: Clerbaux, Laure-Alix, et al.
Publicado: (2019)

Assessment of the predictive capacity of a physiologically based kinetic model using a read-across approach
por: Paini, Alicia, et al.
Publicado: (2021)

From in vitro to in vivo: Integration of the virtual cell based assay with physiologically based kinetic modelling
por: Paini, Alicia, et al.
Publicado: (2017)

Role of Physiologically Based Kinetic modelling in addressing environmental chemical mixtures – A review
por: Desalegn, Anteneh, et al.
Publicado: (2019)

Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications
por: Paini, Alicia, et al.
Publicado: (2017)

Application of physiologically based pharmacokinetic modeling for sertraline dosing recommendations in pregnancy
por: George, Blessy, et al.
Publicado: (2020)

Open forensic science(*)
por: Chin, Jason M, et al.
Publicado: (2019)

Gaining acceptance in next generation PBK modelling approaches for regulatory assessments – An OECD international effort
por: Paini, Alicia, et al.
Publicado: (2021)

An overview to the investigative approach to species testing in wildlife forensic science
por: Linacre, Adrian, et al.
Publicado: (2011)

Translatability and transferability of in silico models: Context of use switching to predict the effects of environmental chemicals on the immune system
por: Pappalardo, Francesco, et al.
Publicado: (2022)

Utilization of Physiologically Based Pharmacokinetic Modeling in Pharmacokinetic Study of Natural Medicine: An Overview
por: Jia, Qiuyu, et al.
Publicado: (2022)

Physiologically based kinetic (PBK) modelling and human biomonitoring data for mixture risk assessment
por: Pletz, Julia, et al.
Publicado: (2020)

Overview of special issue: Human factors in forensic science practice sourcebook
por: Eldridge, Heidi, et al.
Publicado: (2022)

The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data – A case study with caffeine
por: Bessems, Jos G.M., et al.
Publicado: (2017)

Forensic Science Regulator: The Forensic Science Regulator Act 2021
por: Samuels, Alec
Publicado: (2022)

Utilization of Physiologically Based Pharmacokinetic Modeling in Clinical Pharmacology and Therapeutics: an Overview
por: Perry, Courtney, et al.
Publicado: (2020)

Computational modelling and simulation for immunotoxicity prediction induced by skin sensitisers
por: Russo, Giulia, et al.
Publicado: (2022)

Evolution of forensic odontology: An overview
por: Balachander, N., et al.
Publicado: (2015)

Women in Forensics: An international overview
por: Barbaro, Anna
Publicado: (2019)

The use of insects in forensic investigations: An overview on the scope of forensic entomology
por: Joseph, Isaac, et al.
Publicado: (2011)

Reimagining forensic science – The mission of the forensic laboratory
por: Wickenheiser, Ray A.
Publicado: (2021)

Encyclopedia of forensic sciences /
Publicado: (2000)

Virtual Cell Based Assay simulations of intra-mitochondrial concentrations in hepatocytes and cardiomyocytes
por: Worth, Andrew P., et al.
Publicado: (2017)

Forensic science : a beginner's guide /
por: Siegel, Jay A.

Medicine as a forensic science
por: García-Garduza, Ismael
Publicado: (2019)

Forensic science: defending justice
por: Shen, Min, et al.
Publicado: (2016)

Registered reports in forensic science
por: Houck, M. M., et al.
Publicado: (2022)

The scientific reinvention of forensic science
por: Koehler, Jonathan J., et al.
Publicado: (2023)

Journals on legal and forensic medicine in Web of Science Core Collection: focus on Forensic Sciences Research
por: Zhang, Hui, et al.
Publicado: (2021)

Combining in vitro assays and mathematical modelling to study developmental neurotoxicity induced by chemical mixtures
por: Pistollato, Francesca, et al.
Publicado: (2021)

Chiral Drug Analysis in Forensic Chemistry: An Overview
por: Ribeiro, Cláudia, et al.
Publicado: (2018)

An overview of the digital forensic investigation infrastructure of Ghana
por: Apau, Richard, et al.
Publicado: (2020)

U.S. initiatives to strengthen forensic science & international standards in forensic DNA
por: Butler, John M.
Publicado: (2015)

Forensic intelligence: Data analytics as the bridge between forensic science and investigation
por: Delgado, Yaneisy, et al.
Publicado: (2021)

Arylcyclohexylamine Derivatives: Pharmacokinetic, Pharmacodynamic, Clinical and Forensic Aspects
por: Pelletier, Romain, et al.
Publicado: (2022)

Bioarcheology: Medicine, Biology, and Forensic Sciences
por: Appenzeller, Otto, et al.
Publicado: (2015)

Virtopsy: An integration of forensic science and imageology
por: Joseph, T. Isaac, et al.
Publicado: (2017)

Molecular Imprinting Applications in Forensic Science
por: Yılmaz, Erkut, et al.
Publicado: (2017)

The development of forensic science standards in China
por: Zhai, Wanfeng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qd0cgja4c981a8fhb63osnf3sf